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B7 Antigens

Known as: B7 Molecules, B7 antigen, B 7 Antigen 
A family of cell-surface proteins found on ANTIGEN-PRESENTING CELLS. B7 antigens are ligands for specific cell surface receptor subtypes found on T… 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (3)

CD80 AntigensNCR3LG1 protein, humanSkint2 protein, mouse
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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Highly Cited
2013
Highly Cited
2013
B7-H5 costimulates human T cells via CD28H
The B7/CD28 family has profound modulatory effects in immune responses and constitutes an important target for the development of… 
Highly Cited
2007
Highly Cited
2007
Prevaccine determination of the expression of costimulatory B7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults.
BACKGROUND Innate immunity, including Toll-like receptor (TLR)-mediated expression of the B7 costimulatory molecules CD80 and… 
Highly Cited
2006
Highly Cited
2006
T-cell costimulation--biology, therapeutic potential, and challenges.
The pivotal role of costimulation in regulating T-cell activation versus tolerance has stimulated great interest. Drs. Arlene… 
Highly Cited
1999
Highly Cited
1999
Studies in B7-Deficient Mice Reveal a Critical Role for B7 Costimulation in Both Induction and Effector Phases of Experimental Autoimmune Encephalomyelitis
The importance of B7 costimulation in regulating T cell expansion and peripheral tolerance suggests that it may also play a… 
Review
1999
Review
1999
The role of B7 costimulation in T‐cell immunity
CD4+ T cells are considered to be the major controlling element of the adaptive immune response. They recognize foreign peptides… 
Highly Cited
1997
Highly Cited
1997
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.
Highly Cited
1997
Highly Cited
1997
Costimulation of CD28- T lymphocytes by 4-1BB ligand.
The interaction of the T cell surface protein CD28 with its ligand, B7-1 or B7-2, provides a critical costimulatory signal for T… 
Highly Cited
1996
Highly Cited
1996
Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients.
We have shown previously that granulocyte-macrophage colony-stimulating factor-stimulated mouse bone marrow-derived MHC class II… 
Highly Cited
1995
Highly Cited
1995
A reassessment of the role of B7-1 expression in tumor rejection
Introduction of the B7-1 gene into murine tumor cells can result in rejection of the B7-1 transductants and, in some cases… 
Highly Cited
1987
Highly Cited
1987
B7, a B-cell-restricted antigen that identifies preactivated B cells.
After activation with antigen or mitogen, a number of cell surface proteins appear that are not expressed on resting B cells. To… 
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