CD28 Antigens

Known as: TP44 Receptor, Antigens, CD28, CD28 
Costimulatory T-LYMPHOCYTE receptors that have specificity for CD80 ANTIGEN and CD86 ANTIGEN. Activation of this receptor results in increased T-cell… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2017
0102019872017

Papers overview

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Highly Cited
2010
Highly Cited
2010
To enhance the strength of activation afforded by tumor antigen-specific receptors, we investigated the effect of adding combined… (More)
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Highly Cited
1998
Highly Cited
1998
Although multiple sclerosis (MS) patients and healthy individuals have similar frequencies of myelin basic protein (MBP)-specific… (More)
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Highly Cited
1996
Highly Cited
1996
Ageing is associated with complex remodelling in the phenotypic and functional profiles of T lymphocytes. We investigated whether… (More)
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Highly Cited
1996
Highly Cited
1996
T cell activation requires at least two distinct signals, including signaling via the Ag-specific TCR and a costimulatory pathway… (More)
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Highly Cited
1996
Highly Cited
1996
CD28 has been demonstrated to play an important role in augmenting T cell proliferation and effector function. Costimulation… (More)
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1996
1996
T cells require two distinct signals for optimal activation. One is an antigen-specific signal and is provided by engagement of… (More)
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Highly Cited
1993
Highly Cited
1993
T cell receptor stimulation without costimulation is insufficient for the induction of an optimal immune response. It is thought… (More)
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Highly Cited
1991
Highly Cited
1991
A successful immune response requires intercellular contact between T and B lymphocytes. We recently showed that CD28, a T cell… (More)
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Highly Cited
1991
Highly Cited
1991
Occupancy of the T-cell receptor complex does not appear to be a sufficient stimulus to induce a T-cell-mediated immune response… (More)
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Highly Cited
1987
Highly Cited
1987
CD28 is a homodimeric glycoprotein expressed on the surface of a major subset of human T cells that has recently been identified… (More)
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