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CD28 Antigens

Known as: TP44 Receptor, Antigens, CD28, CD28 
Costimulatory T-LYMPHOCYTE receptors that have specificity for CD80 ANTIGEN and CD86 ANTIGEN. Activation of this receptor results in increased T-cell… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
To study the cis- and trans-acting factors that mediate programmed death 1 (PD-1) signaling in primary human CD4 T cells, we… Expand
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Highly Cited
2002
Highly Cited
2002
Signals generated by T cell receptor (TCR) and CD28 engagement are required for optimal T cell activation, but how these signals… Expand
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Highly Cited
2001
Highly Cited
2001
Recombinant immunoreceptors with specificity for the carcinoembryonic Ag (CEA) can redirect grafted T cells to a MHC/Ag… Expand
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Highly Cited
2000
Highly Cited
2000
CD28 and CTLA-4 are related members of a family of T lymphocyte cell surface receptors that function to regulate T cell… Expand
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Highly Cited
1995
Highly Cited
1995
The importance of the B7/CD28/CTLA-4 molecules has been established in studies of antigen-presenting cell-derived B7 and its… Expand
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Highly Cited
1995
Highly Cited
1995
T cell activation through the TCR can result in either cell proliferation or cell death. The role of costimulatory receptors in… Expand
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Highly Cited
1995
Highly Cited
1995
The importance of CD28 costimulation to a primary T cell response in vivo was assessed in an adoptive transfer system where a… Expand
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Highly Cited
1991
Highly Cited
1991
CD4+ T cells require two signals to produce maximal amounts of IL-2, i.e., TCR occupancy and an unidentified APC-derived… Expand
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Highly Cited
1989
Highly Cited
1989
CD28 is a 44-kDa glycoprotein expressed as a homodimer on the surface of a major subset of human T cells. Previous studies have… Expand
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Highly Cited
1987
Highly Cited
1987
CD28 is a homodimeric glycoprotein expressed on the surface of a major subset of human T cells that has recently been identified… Expand
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