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AB103

Known as: AB103 peptide, SPMLVAYD, p2TA peptide 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

CD28 Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Interventions for necrotizing soft tissue infections in adults.
BACKGROUND Necrotizing soft tissue infections (NSTIs) are severe and rapidly spreading soft tissue infections of the subcutaneous… 
2015
2015
Excess of Rare Variants in Genes that are Key Epigenetic Regulators of Spermatogenesis in the Patients with Non-Obstructive Azoospermia
Non-obstructive azoospermia (NOA), a severe form of male infertility, is often suspected to be linked to currently undefined… 
2015
2015
CD28 homodimer interface mimetic peptide acts as a preventive and therapeutic agent in models of severe bacterial sepsis and gram-negative bacterial peritonitis.
BACKGROUND Severe gram-negative bacterial infections and sepsis are major causes of morbidity and mortality. Dysregulated… 
Highly Cited
2014
Highly Cited
2014
A Novel Drug for Treatment of Necrotizing Soft-Tissue Infections: A Randomized Clinical Trial.
IMPORTANCE Necrotizing soft-tissue infections (NSTI) have high morbidity and mortality rates despite aggressive surgical… 
2014
2014
Single Administration of p2TA (AB103), a CD28 Antagonist Peptide, Prevents Inflammatory and Thrombotic Reactions and Protects against Gastrointestinal Injury in Total-Body Irradiated Mice
The goal of this study was to elucidate the action of the CD28 mimetic peptide p2TA (AB103) that attenuates an excessive… 
2014
2014
Treatment for Necrotizing Soft-Tissue Infections: More Skin in the Game.
Thearticle byBulger et al1 represents an advance in theworld of surgical infections as the first interventional trial using an… 
Review
2014
Review
2014
AB103. Prostatectomy versus active surveillance for early stage prostate cancer: a meta-analysis
Objective To compare the survival effect between radical prostatectomy (RP) and active surveillance (AS) for the treatment of… 
2013
2013
A peptide antagonist of CD28 signaling attenuates toxic shock and necrotizing soft-tissue infection induced by Streptococcus pyogenes.
Staphylococcus aureus and group A Streptococcus pyogenes (GAS) express superantigen (SAg) exotoxin proteins capable of inducing… 
2011
2011
AB103, a CD28 antagonist peptide: a new therapeutic agent in a model of severe sepsis
AB103 is a novel CD28 antagonist peptide currently in clinical development that modulates CD28 signaling in T cells, without… 
1990
1990
A mathematical description of recombinant yeast
A model was formulated to examine specific experimental data of growth and heterologous product formation with recombinant… 
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