CTLA4 gene

Known as: CD, CYTOTOXIC T LYMPHOCYTE-ASSOCIATED 4, CD28 
This gene is involved in T-cell mediation and receptor signal transduction.
National Institutes of Health

Papers overview

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2015
2015
Allergic asthma is caused by Th2-cell-type cytokines in response to allergen exposure. Type 2 innate lymphoid cells (ILC2s) are a… (More)
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Highly Cited
2014
Highly Cited
2014
The protein cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential negative regulator of immune responses, and its loss causes… (More)
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2012
2012
A progressive waning in Foxp3(+) regulatory T cell (Treg) functions is thought to provoke autoimmunity in the NOD model of type 1… (More)
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Highly Cited
2011
Highly Cited
2011
Grapes have high amounts of phenolic compounds, which can modulate the gut activity as well as modify the structure and function… (More)
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Highly Cited
2009
Highly Cited
2009
IL-27 has recently been identified as a differentiation factor for the generation of IL-10-producing regulatory type 1 (Tr1) T… (More)
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2008
2008
CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore… (More)
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Highly Cited
2003
Highly Cited
2003
Helper T (Th) cell differentiation is accompanied by complex transcriptional changes. Although costimulatory receptors are… (More)
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Review
2002
Review
2002
T cell activation is dependent upon signals delivered through the antigen-specific T cell receptor and accessory receptors on the… (More)
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Highly Cited
2002
Highly Cited
2002
With newly generated ICOS-ligand (ICOS-L)-specific monoclonal antibodies we determined that human Langerhans cells in situ… (More)
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Highly Cited
2001
Highly Cited
2001
The outcome of T-cell responses after T-cell encounter with specific antigens is modulated by co-stimulatory signals, which are… (More)
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