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Azacitidine

Known as: 5-Aza-cytidine, 5 Azacytidine, Azacitidine [Chemical/Ingredient] 
A pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA… 
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (11)

2'-beta-deoxy-6-azacytidine5,6-dihydro-5-azacytidine6-azacytidineCP 4200
AZI2 geneAzacitidine 100 MG Injection [Vidaza]DNA Methylation InhibitionDNA Methyltransferase Inhibitors [MoA]

Broader (5)

Antimetabolites, AntineoplasticAntineoplastic AgentsCytidineEnzyme Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
Clinical and hematological response to hydroxyurea in a patient with Hb Lepore/beta-thalassemia.
The possibility of increasing Hb F in vivo using drugs like 5-azacytidine, hydroxyurea, and butyrate has been established… 
1986
1986
Arabinofuranosyl-5-azacytosine: antitumor and cytotoxic properties.
Arabinofuranosyl-5-azacytosine (ara-AC), a nucleoside combining the structural elements of 5-azacytidine and… 
1984
1984
DNA methylation and expression of HLA-DR alpha
B-cell lines established from two individuals with T-cell acute lymphocytic leukemia (T-ALL) express HLA-DR antigens, whereas the… 
1984
1984
A new murine model system for the in vitro development of thymoma cell heterogeneity.
We have established and characterized a continuous T-cell line derived from the bone marrow of an AKR mouse with disseminated… 
1979
1979
Synthesis and antitumor activity of 5-azacytosine arabinoside.
5-Azacytosine arabinoside (ara-AC) can be considered a combination of structural elements derived from the antitumor nucleosides… 
1979
1979
Metabolism and effects of 5-(beta-D-ribofuranosyl)isocytosine in P815 cells.
5-(beta-D-Ribofuranosyl)isocytosine (psi l Cyd), a C-nucleoside, has been shown to be active against P815 leukemia in mice. In… 
1978
1978
Increased survival in childhood acute nonlymphocytic leukemia after treatment with prednisone, cytosine arabinoside, 6-thioguanine, cyclophosphamide, and oncovin (PATCO) combination chemotherapy.
One hundred-sixty-three children with acute nonlymphocytic leukemia (ANLL) were treated with a multiple-drug induction program… 
1977
1977
Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine.
5,6-Dihydro-5-azacytidine hydrochloride, a chemically stable, soluble analog of 5-azacytidine, has cytostatic activity against… 
1973
1973
Depression of polyamine synthesis in L1210 leukemic mice during treatment with a potent antileukemic agent, 5-azacytidine.
Summary Polyamine metabolism was studied in spleens and livers of BDF1 mice after i.p. inoculations of 106 L1210 leukemic cells… 
1971
1971
Inhibition of isoproterenol-stimulated deoxyribonucleic acid synthesis by 5-azacytidine.