Azacitidine

Known as: 5-Aza-cytidine, 5 Azacytidine, Azacitidine [Chemical/Ingredient] 
A pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
This multicenter, randomized, open-label, phase 3 trial evaluated azacitidine efficacy and safety vs conventional care regimens… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE In a phase III randomized trial, azacitidine significantly prolonged overall survival (OS) compared with conventional… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Recurrence is a major cause of treatment failure after allogeneic transplantation for acute myelogenous leukemia (AML… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Drug treatments for patients with high-risk myelodysplastic syndromes provide no survival advantage. In this trial, we… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment with surgery… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Within the last two decades, a new understanding of the biology of myelodysplastic syndrome (MDS) has developed. With… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE This article summarizes data submitted to the U.S. Food and Drug Administration for marketing approval of azacitidine as… (More)
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Highly Cited
2004
Highly Cited
2004
The Wharton's jelly of the umbilical cord contains mucoid connective tissue and fibroblast-like cells. Using flow cytometric… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE Patients with high-risk myelodysplastic syndrome (MDS) have high mortality from bone marrow failure or transformation to… (More)
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Highly Cited
1987
Highly Cited
1987
5-azacytidine treatment of mouse C3H10T1/2 embryonic fibroblasts converts them to myoblasts at a frequency suggesting alteration… (More)
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