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Azacitidine

Known as: 5-Aza-cytidine, 5 Azacytidine, Azacitidine [Chemical/Ingredient] 
A pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA… 
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (11)

2'-beta-deoxy-6-azacytidine5,6-dihydro-5-azacytidine6-azacytidineCP 4200
AZI2 geneAzacitidine 100 MG Injection [Vidaza]DNA Methylation InhibitionDNA Methyltransferase Inhibitors [MoA]

Broader (5)

Antimetabolites, AntineoplasticAntineoplastic AgentsCytidineEnzyme Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Enasidenib Plus Azacitidine Significantly Improves Complete Remission and Overall Response Compared with Azacitidine Alone in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) with…
Background: Mutations in IDH2 occur in 8-19% of patients (pts) with AML. Enasidenib (ENA; AG-221) is an oral, small-molecule… 
2010
2010
Proteome analysis of rat bone marrow mesenchymal stem cell differentiation.
Bone marrow multipotent stromal cells (or mesenchymal stem cells; MSCs) have the capacity for renewal and the potential to… 
1985
1985
X chromosome reactivation in mouse embryonal carcinoma cells
The embryonal carcinoma cell line, C86S1, carries two X chromosomes, one of which replicates late during S phase of the cell… 
1984
1984
Reversal of DNA methylation with 5-azacytidine alters chromosome replication patterns in human lymphocyte and fibroblast cultures.
Prior studies demonstrated that developmental or induced methylation of DNA can inactivate associated gene loci. Such DNA… 
1981
1981
Effect of schedule on activity and toxicity of 5‐azacytidine in acute leukemia: A southwest oncology group study
One‐hundred‐fifty‐four patients with acute leukemia and extensive prior chemotherapy were treated with 5‐Azacytidine and… 
1979
1979
Synthesis and antitumor activity of 5-azacytosine arabinoside.
5-Azacytosine arabinoside (ara-AC) can be considered a combination of structural elements derived from the antitumor nucleosides… 
1978
1978
Increased survival in childhood acute nonlymphocytic leukemia after treatment with prednisone, cytosine arabinoside, 6-thioguanine, cyclophosphamide, and oncovin (PATCO) combination chemotherapy.
One hundred-sixty-three children with acute nonlymphocytic leukemia (ANLL) were treated with a multiple-drug induction program… 
1978
1978
Metabolism and cytotoxicity of 5-azacytidine in cultured Novikoff rat hepatoma and P388 mouse leukemia cells and their enhancement by preincubation with pyrazofurin.
5-Azacytidine transport into cells was measured in the absence of metabolism in adenosine triphosphate-depleted and uridine… 
1972
1972
Latency of Human Measles Virus in Hamster Cells
A latent system employing measles virus (Schwarz strain) was developed in hamster embryo fibroblasts (HEF). Measles virus… 
Highly Cited
1968
Highly Cited
1968
Characteristics of mouse leukemic cells resistant to 5-azacytidine and 5-aza-2'-deoxycytidine.
Summary During the development of resistance to 5-azacytidine, AKR mouse leukemic cells incorporated significantly less cytidine… 
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