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Enzyme Inhibitors
Known as:
Inhibitors, Enzyme
, enzyme inhibitor
, enzymes inhibitors
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
National Institutes of Health
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3-chlorotyrosine
5-iodotubercidin
7-ketocholesterol
Acetyldigitoxins
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Highly Cited
1989
Highly Cited
1989
CGP 38 560: Orally Active, Low‐Molecular‐Weight Renin Inhibitor with High Potency and Specificity
J. Wood
,
L. Criscione
,
+5 authors
J. Kay
Journal of Cardiovascular Pharmacology
1989
Corpus ID: 41810399
CGP 38 560 is a low-molecular-weight (730) inhibitor of human renin that contains only one natural amino acid. In vitro, it is a…
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1985
1985
Effect of chronic nifedipine in patients inadequately controlled by a converting enzyme inhibitor and a diuretic.
A. Mimran
,
J. Ribstein
Journal of Cardiovascular Pharmacology
1985
Corpus ID: 30879610
Nifedipine, in a slow release preparation, was given at a mean daily dosage of 47 +/- 4 mg to 12 patients with severe…
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1985
1985
A dose-response study of HOE 498, a new non-sulphydryl converting enzyme inhibitor, on blood pressure, pulse rate and the renin-angiotensin-aldosterone system in normal man.
P. Manhem
,
S. Ball
,
+5 authors
J. Robertson
British Journal of Clinical Pharmacology
1985
Corpus ID: 23737521
The effect of different oral doses of HOE 498, a new non-sulphydryl containing converting enzyme inhibitor, was investigated in a…
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1984
1984
Stimulation of granulocyte functions in vitro by imipenem and the renal enzyme inhibitor MK 0791
Håkan Gnarpe
,
J. Belsheim
,
C. Blomqvist
,
Annika Lundback
Antimicrobial Agents and Chemotherapy
1984
Corpus ID: 38909767
Imipenem and the renal enzyme inhibitor MK 0791 (dehydropeptidase-I) were tested separately and in a 1:1 combination to delineate…
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1983
1983
Pharmacological properties of the converting enzyme inhibitor, enalapril maleate (MK-421).
Sweet Cs
1983
Corpus ID: 91694521
: Enalapril maleate (MK-421), an ethyl ester, is an angiotensin-converting enzyme (ACE) inhibitor from a novel series of…
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1983
1983
Retrostatin, a new specific enzyme inhibitor against avian myeloblastosis virus reverse transcriptase.
M. Nishio
,
A. Kuroda
,
M. Suzuki
,
K. Ishimaru
,
S. Nakamura
,
R. Nomi
Journal of antibiotics (Tokyo. )
1983
Corpus ID: 31215234
A novel enzyme inhibitor against RNA-directed DNA polymerase of avian myeloblastosis virus was produced by an isolate of a new…
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Highly Cited
1980
Highly Cited
1980
The Antihypertensive Effect of Captopril
A. Mimran
,
R. Targhetta
,
B. Laroche
HYPERTENSION
1980
Corpus ID: 116987
SUMMARY The acute effect of the orally-active converting enzyme inhibitor, captopril, was compared to that of saralasin in 13…
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Highly Cited
1969
Highly Cited
1969
1-Anilinonaphthalene-8-sulphonate, a fluorescent conformational probe for glutamate dehydrogenase.
Doddgh
,
G. Radda
Biochemical Journal
1969
Corpus ID: 27281876
1. The interaction of 1-anilinonaphthalene-8-sulphonate with ox liver glutamate dehydrogenase was examined. 2. The fluorescence…
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1968
1968
131-I-3'-iodoaminopterin: a gamma-labeled active-site-directed enzyme inhibitor.
D. Johns
,
R. P. Spencer
,
P. K. Chang
,
J. Bertino
Journal of Nuclear Medicine
1968
Corpus ID: 41872411
format: Exhibitor's Name: Underline responsible exhibitor. Title of Exhibit: 10 words maximum. Abstract: 200 words. Dimensions…
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1965
1965
ACUTE EXPERIMENTAL PANCREATITIS: ROLE OF A PROTEOLYTIC ENZYME INHIBITOR IN TREATMENT.
A. Schutt
,
K. Wakim
,
L. G. Bartholomew
,
J. Cain
,
A. Baggenstoss
Journal of the American Medical Association (JAMA…
1965
Corpus ID: 40423491
An antitryptic agent (Trasylol), a polyvalent proteolytic enzyme inhibitor, was used to treat four types of experimental…
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