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3-chlorotyrosine

Known as: L-(8CI)-3-Chloro-Tyrosine, Cl-Tyr, Monochlorotyrosine 
A specific biomarker of hypochlorous acid (HClO), the oxidation product of myeloperoxidase (MPO). Under oxidative stress, 3-chlorotyrosine is… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Enzyme InhibitorsTyrosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Biomarkers of Neutrophil-Mediated Glutathione and Protein Oxidation in Tracheal Aspirates From Preterm Infants: Association With Bacterial Infection
Bronchopulmonary dysplasia is associated with neutrophil infiltration into the lungs and oxidative injury. However, the… 
2009
2009
Development of novel mass spectrometric methods for identifying HOCl‐induced modifications to proteins
Protein oxidation is thought to contribute to a number of inflammatory diseases, hence the development of sensitive and specific… 
2004
2004
Urinary eicosanoid and tyrosine derivative concentrations in patients with vasculitides.
2003
2003
Functional significance of inducible nitric oxide synthase induction and protein nitration in the thermally injured cutaneous microvasculature.
Highly Cited
2002
Highly Cited
2002
Elevated Free Radical Products in the Cerebrospinal Fluid of VLBW Infants with Cerebral White Matter Injury
Free radical mediated cellular injury has been hypothesized to play a key role in the pathogenesis of white matter injury in the… 
Review
2002
Review
2002
Myeloperoxidase-mediated Protein Oxidation: Its Possible Biological Functions
Abstract Oxidation of proteins occurs both as a side-effect of aerobic energy metabolism and as an effect of specific metabolism… 
1996
1996
Oxidative modification of ovalbumin.
Stimulated neutrophils (PMNL) are a source of the active oxygen species: O2, H2O2 and HOCl/OCl- which in turn can act on proteins… 
1984
1984
Halogenated tyrosine derivatives in invertebrate scleroproteins: isolation and identification.
1974
1974
Inhibition of phenylalanine hydroxylase by p-chlorophenylalanine; dependence on cofactor structure.
1972
1972
Halogenated tyrosines from the cuticle of Limulus polyphemus (L.).
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