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A comprehensive conformational analysis of isolated 2'-beta-deoxy-6-azacytidine (d6AC), an analogue of therapeutically active 6… Expand 6-azacytidine demonstrates activity against adenoviruses types 1, 2, 5. It inhibit synthesis of viral DNA and proteins. 6-AC… Expand Several N4-derivatives of 6-azacytidine were synthesized using of Vorbrüggen's condensation method. Their antiviral activity with… Expand Methylation of cytosine residues in mammalian DNA is established during gametogenesis and embryogenesis; it plays an important… Expand Absent expression of the cyclin dependent kinase-inhibitor, p16INK4, is observed in a wide range of primary human cancers… Expand Jones and coworkers demonstrated a qualitative correlation between 5-azacytidine and some of its analogs in inducing changes in… Expand The ability of the hypomethylating agent 5-azacytidine to transform normal primary rat tracheal epithelial cells was determined… Expand To determine whether 5-azacytidine (5-AzaCR)-induced transformation and/or differentiation of C3H/10T 1/2 clone B (10T 1/2) cells… Expand The nucleoside analog 5-azacytidine (5-aza-CR) induced marked changes in the differentiated state of cultured mouse embryo cells… Expand Abstract The acute toxicity of 6-azauridine and 6-azacytidine after intraperitoneal injection in mice is very low. After repeated… Expand