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Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals.
The assay was incapable of providing a clear indication of whether some chemicals were mutagens; these were benzyl alcohol, 1,4-dichlorobenzene, phenol, succinic acid-2,2-dimethyl hydrazide, and toluene.
TFT and 6TG resistance of mouse lymphoma cells to analogs of azacytidine.
In L5178Y mouse lymphoma (MOLY) cells, 5-aza-CR induced TFT resistance and produced both small and large colonies, and the different spectrum of DNA lesions detected at the tk locus may be responsible for the response of MOLY cells to 5-az-CR.