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DNA Methylation Inhibition

DNA Methylation Inhibition involves interference with, or restraint of, the process by which methyl groups are added to genomic DNA nucleotides.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
DNA methylation aberrancies are hallmarks of human cancers and are characterized by global DNA hypomethylation of repetitive… Expand
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Highly Cited
2015
Highly Cited
2015
BackgroundDNA methylation plays an important role in regulating gene expression during many biological processes. However, the… Expand
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Review
2014
Review
2014
heart failure Yu-Hsun Kao , Gi-Shih Lien , Tze-Fan Chao , Yi-Jen Chen b,e,⁎ a Department of Medical Education and Research, Wan… Expand
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2013
2013
AbstractA variety of environmental pollutants may cause abnormal DNA methylation, which further disturb gene expression. In this… Expand
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Highly Cited
2010
Highly Cited
2010
DNA methyltransferases (DNMTs) represent promising targets for the development of unique anticancer drugs. However, all DNMT… Expand
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2009
2009
Killer-cell immunoglobulin-like receptor (KIR) genes are a polymorphic family expressed on NK cells, and "senescent" CD28- T… Expand
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2007
2007
Azacitidine and decitabine are cytidine analogues that inhibit DNA methylation, and are used to treat myeloid haematological… Expand
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Highly Cited
2005
Highly Cited
2005
DNA cytosine methylation plays a considerable role in normal development, gene regulation, and carcinogenesis. Hypermethylation… Expand
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Highly Cited
2003
Highly Cited
2003
Perforin is a cytotoxic effector molecule expressed in NK cells and a subset of T cells. The mechanisms regulating its expression… Expand
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2001
2001
We hypothesize that elevation of Nm23-H1 expression in micrometastatic breast cancer cells may inhibit their metastatic… Expand
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