DNA Methylation Inhibition

DNA Methylation Inhibition involves interference with, or restraint of, the process by which methyl groups are added to genomic DNA nucleotides.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
02419972016

Papers overview

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2015
2015
DNA methylation plays an important role in regulating gene expression during many biological processes. However, the mechanism of… (More)
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2014
2013
2013
A variety of environmental pollutants may cause abnormal DNA methylation, which further disturb gene expression. In this work, we… (More)
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2010
2010
DNA methyltransferases (DNMTs) represent promising targets for the development of unique anticancer drugs. However, all DNMT… (More)
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2009
2009
Killer-cell immunoglobulin-like receptor (KIR) genes are a polymorphic family expressed on NK cells, and "senescent" CD28- T… (More)
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2007
2007
Azacitidine and decitabine are cytidine analogues that inhibit DNA methylation, and are used to treat myeloid haematological… (More)
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Highly Cited
2005
Highly Cited
2005
DNA cytosine methylation plays a considerable role in normal development, gene regulation, and carcinogenesis. Hypermethylation… (More)
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Highly Cited
2003
Highly Cited
2003
Perforin is a cytotoxic effector molecule expressed in NK cells and a subset of T cells. The mechanisms regulating its expression… (More)
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2001
2001
We hypothesize that elevation of Nm23-H1 expression in micrometastatic breast cancer cells may inhibit their metastatic… (More)
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1997
1997
DNA methylation, a mechanism modifying gene expression, is mediated in part by the enzyme DNA methyltransferase. Reduced levels… (More)
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