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DNA Methyltransferase Inhibitors [MoA]

Known as: DNA Methyltransferase Inhibitors, DNA Methytransferase Inhibitors 
National Institutes of Health

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2 relations
AzacitidineDNA Methyltransferase Inhibitor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Epigenetic Therapeutics and Their Impact in Immunotherapy of Lung Cancer
Lung cancer is the leading cause of cancer-related death in the USA and worldwide. Novel therapeutic developments are critically… 
2017
2017
DNA methyltransferase inhibitors influence on the DIRAS3 and STAT3 expression and in vitro migration of ovarian and breast cancer cells.
OBJECTIVES Downregulation of DIRAS3 (DIRAS family, GTP-binding Ras-like 3) is related to ovarian and breast cancer progression. A… 
2016
2016
Clinical Impact of Hypomethylating Agents in the Treatment of Myelodysplastic Syndromes.
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic diseases, mainly affecting the elderly, characterized by… 
2015
2015
Computational fishing of new DNA methyltransferase inhibitors from natural products.
Review
2015
Review
2015
The clinical use of DNA methyltransferase inhibitors in myelodysplastic syndromes
Myelodysplastic syndromes (MDS) include a heterogeneous group of acquired hematopoietic malignancies characterized by ineffective… 
Review
2015
Review
2015
Epigenetic therapy for colorectal cancer.
Aberrations in epigenome that include alterations in DNA methylation, histone acetylation, and miRNA (microRNA) expression may… 
2014
2014
Ingenol derivates promising for HIV eradication.
The eradication of HIV is at this moment one of the greatest challenges in the fight against HIV/AIDS. Despite the prolonged… 
2011
2011
Epigenetic manipulation of the immune response: a novel treatment strategy in hematologic malignancies.
Acquired abnormalities in chromatin structure are increasingly recognized as an important mechanism of leukemogenesis. In… 
Review
2010
Review
2010
Prior Therapy with DNA Methyltransferase Inhibitors (DNMTI) Predicts for Lower Remission Rates and Worse Survival In Secondary Acute Myeloid Leukemia Patients (sAML) Receiving Remission Induction…
Abstract 4033 Background: DNMTIs are the most commonly used disease modifying agents for myelodysplastic syndromes (MDS… 
2007
2007
Targets of epigenetic therapy – Gene reactivation as a novel approach in MDS treatment
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