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DNA Methyltransferase Inhibitors [MoA]

Known as: DNA Methyltransferase Inhibitors, DNA Methytransferase Inhibitors 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Vitamin C deficiency is found in patients with cancer and might complicate various therapy paradigms. Here we show how this… Expand
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Highly Cited
2015
Highly Cited
2015
We show that DNA methyltransferase inhibitors (DNMTis) upregulate immune signaling in cancer through the viral defense pathway… Expand
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Highly Cited
2015
Highly Cited
2015
We show that DNA methyltransferase inhibitors (DNMTis) upregulate immune signaling in cancer through the viral defense pathway… Expand
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Highly Cited
2015
Highly Cited
2015
Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in genes encoding epigenetic… Expand
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2015
2015
Mutations in IDH1 and IDH2 occur in 15-20% of AML cases, resulting in the production of 2-hydroxyglutarate, which promotes… Expand
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2014
2014
Different epigenetic alterations (DNA methylation, histone modifications, chromatin remodeling, noncoding RNA dysregulation) are… Expand
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2014
2014
DNA methyltransferase inhibitors (DNMTi) and histone deacetylase inhibitors (HDACi) are under investigation for the treatment of… Expand
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2013
2013
Epigenetic alterations are a hallmark of cancer that govern the silencing of genes. Up to now, 5-azacytidine (5-aza-CR, Vidaza… Expand
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2011
2011
DNA methylation plays an important role in carcinogenesis and the reversibility of this epigenetic modification makes it a… Expand
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2011
2011
Background:Epigenetic mechanisms have important roles in the tumour escape from immune responses, such as in MHC class I… Expand
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