DNA Methyltransferase Inhibitor

Known as: DNMT Inhibitor 
Any substance that inhibits DNA methyltransferase, an enzyme required for DNA methylation. Inhibition of DNA methyltransferase results in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2016
0520032016

Papers overview

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2015
2015
Alteration of DNA methylation is highly associated with ageing and ageing-related diseases. Remedy of the altered methylation… (More)
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2015
2015
Drug addiction is considered an aberrant form of learning, and drug-associated memories evoked by the presence of associated… (More)
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2014
2014
Increasing evidence suggests that dysfunction of histone lysine demethylase is associated with abnormal chromatin remodeling and… (More)
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2013
2013
Epigenetic gene silencing, mediated by aberrant promoter DNA hypermethylation and repressive histone modifications, is a hallmark… (More)
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2012
2012
Gemcitabine is indicated in combination with cisplatin as first-line therapy for solid tumours including non-small… (More)
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Highly Cited
2012
Highly Cited
2012
Acute myeloid leukemia (AML) is a disease of the elderly, affecting patients with a median age of 65--70 years. Cytotoxic… (More)
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2012
2012
We have characterized the uterine expression of DNA methyltransferases (DNMTs) during early pregnancy in mice and determined… (More)
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2010
2010
Cooperating leukemogenic events in MLL-rearranged (MLL-r) infant acute lymphoblastic leukemia (ALL) are largely unknown. We… (More)
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2010
2010
Malignant melanoma cells express the vitamin D receptor (VDR). However, some melanoma cell lines fail to respond to the… (More)
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Highly Cited
2003
Highly Cited
2003
In t(8;21) acute myeloid leukemia (AML), the AML1/ETO fusion protein promotes leukemogenesis by recruiting histone deacetylase… (More)
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