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Arylamine N-Acetyltransferase

Known as: Acetyl-CoA Arylamine N-Acetyltransferase, Arylamine N Acetyltransferase, Acetyl-CoA:arylamine N-acetyltransferase 
An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also catalyze acetyl transfer between arylamines without… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
A set of three N,N-di-p-methoxyphenylamine-substituted pyrene derivatives have successfully been synthesized and characterized by… Expand
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Highly Cited
2003
Highly Cited
2003
Comparative two-dimensional proteome analysis was used to identify proteins differentially expressed in multiple clinical normal… Expand
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Review
2000
Review
2000
Arylamine N:-acetyltransferase (NAT) was first identified as the inactivator of the anti-tubercular drug isoniazid. The enzyme… Expand
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Highly Cited
2000
Highly Cited
2000
Arylamine N-acetyltransferase-1 (NAT1) is a polymorphically expressed enzyme that is widely distributed throughout the body. In… Expand
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Highly Cited
1998
Highly Cited
1998
The study of placental xenobiotic metabolism is important for the determination of foetal exposure to environmental chemicals as… Expand
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Highly Cited
1995
Highly Cited
1995
Abstract The reaction of aryl halides with secondary amines in the presence of silylamide base and tri- o -tolyphopshine… Expand
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Highly Cited
1994
Highly Cited
1994
The metabolic activation of food-borne heterocyclic amines to colon carcinogens in humans is hypothesized to occur via N… Expand
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Highly Cited
1990
Highly Cited
1990
To elucidate the molecular basis of human N-acetylation polymorphism, cDNA clones encoding human liver N-acetyltransferases (EC 2… Expand
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Highly Cited
1983
Highly Cited
1983
Hepatic N-oxidation, followed by N-glucuronidation, has been proposed as a route of metabolic activation for arylamine bladder… Expand
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Highly Cited
1980
Highly Cited
1980
  • H. Hamm, M. Menaker
  • Proceedings of the National Academy of Sciences…
  • 1980
  • Corpus ID: 6510965
There is a large-amplitude circadian rhythm of indoleamine metabolism in the retina-pigment epithelium of the chicken. N… Expand
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