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A set of three N,N-di-p-methoxyphenylamine-substituted pyrene derivatives have successfully been synthesized and characterized by… Expand The identification, synthesis and evaluation of a series of rhodanine and thiazolidin-2,4-dione derivatives as selective… Expand Arylamine N-acetyltransferase-1 (NAT1) is a polymorphically expressed enzyme that is widely distributed throughout the body. In… Expand Arylamine N:-acetyltransferase (NAT) was first identified as the inactivator of the anti-tubercular drug isoniazid. The enzyme… Expand This article is a report on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics… Expand Abstract The reaction of aryl halides with secondary amines in the presence of silylamide base and tri- o -tolyphopshine… Expand The metabolic activation of food-borne heterocyclic amines to colon carcinogens in humans is hypothesized to occur via N… Expand To elucidate the molecular basis of human N-acetylation polymorphism, cDNA clones encoding human liver N-acetyltransferases (EC 2… Expand Hepatic N-oxidation, followed by N-glucuronidation, has been proposed as a route of metabolic activation for arylamine bladder… Expand There is a large-amplitude circadian rhythm of indoleamine metabolism in the retina-pigment epithelium of the chicken. N… Expand