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Arylamine N-Acetyltransferase
Known as:
Acetyl-CoA Arylamine N-Acetyltransferase
, Arylamine N Acetyltransferase
, Acetyl-CoA:arylamine N-acetyltransferase
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An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also catalyze acetyl transfer between arylamines without…
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National Institutes of Health
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Related topics
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14 relations
In Blood
N-hydroxyarylamine O-acetyltransferase
NAT1 gene
NAT2 gene
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Narrower (2)
N-acetyltransferase 1
NAT2 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines.
J. Sandy
,
A. Mushtaq
,
S. Holton
,
P. Schartau
,
M. Noble
,
E. Sim
Biochemical Journal
2005
Corpus ID: 5498075
The NATs (arylamine N-acetyltransferases) are a well documented family of enzymes found in both prokaryotes and eukaryotes. NATs…
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Review
2003
Review
2003
Arylamine N-acetyltransferases: a pharmacogenomic approach to drug metabolism and endogenous function.
E. Sim
,
K. Pintér
,
+4 authors
M. Noble
Biochemical Society Transactions
2003
Corpus ID: 12775589
The arylamine N-acetyltransferases (NATs) are a unique family of enzymes that catalyse the transfer of an acetyl group from…
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2002
2002
Berberine Inhibited Arylamine N-Acetyltransferase Activity and Gene Expression and DNA Adduct Formation in Human Malignant Astrocytoma (G9T/VGH) and Brain Glioblastoma Multiforms (GBM 8401) Cells
D. Y. Wang
,
C. Yeh
,
J. H. Lee
,
C. Hung
,
J. Chung
Neurochemical Research
2002
Corpus ID: 10340341
Studies have demonstrated that berberine exhibits the antineoplastic action in rat model. Rat glial tumor cells also have been…
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2001
2001
Variation in enzymes of arylamine procarcinogen biotransformation among bladder cancer patients and control subjects.
S. Vaziri
,
N. Hughes
,
H. Sampson
,
G. Darlington
,
M. Jewett
,
D. Grant
Pharmacogenetics (London)
2001
Corpus ID: 27081304
Arylamines such as 2-naphthylamine and 4-aminobiphenyl are suspected human bladder procarcinogens that require bioactivation to…
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1991
1991
Functionalized membrane supports for covalent protein microsequence analysis.
J. Coull
,
D. Pappin
,
J. Mark
,
R. Aebersold
,
H. Köster
Analytical Biochemistry
1991
Corpus ID: 34113972
1986
1986
N-hydroxyarylamine O-acetyltransferase in hamster liver: identity with arylhydroxamic acid N,O-acetyltransferase and arylamine N-acetyltransferase.
K. Saito
,
A. Shinohara
,
T. Kamataki
,
R. Kato
Journal of Biochemistry (Tokyo)
1986
Corpus ID: 30489874
N-Hydroxyarylamine O-acetyltransferase, arylhydroxamic acid N,O-acetyltransferase, and arylamine N-acetyltransferase in hamster…
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Highly Cited
1985
Highly Cited
1985
DNA adducts formed from the probable proximate carcinogen, N-hydroxy-3,2' -dimethyl-4-aminobiphenyl, by acid catalysis or S-acetyl coenzyme A-dependent enzymatic esterification.
T. Flammang
,
J. Westra
,
F. Kadlubar
,
F. Beland
Carcinogenesis
1985
Corpus ID: 35360621
The arylamine carcinogen 3,2'-dimethyl-4-aminobiphenyl (DMABP) has been proposed to be metabolically activated to DNA-binding…
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1985
1985
Acetyl coenzyme A-dependent binding of carcinogenic and mutagenic dinitropyrenes to DNA.
Z. Djurić
,
E. Fifer
,
F. Beland
Carcinogenesis
1985
Corpus ID: 11477172
Dinitropyrenes are mutagenic and carcinogenic environmental pollutants found in diesel emissions and urban air particulates. In…
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1983
1983
Purification and physical-chemical properties of acetyl-CoA:arylamine N-acetyltransferase from pigeon liver.
H. Andres
,
H. Kolb
,
L. Weiss
Biochimica et Biophysica Acta
1983
Corpus ID: 8036338
Highly Cited
1957
Highly Cited
1957
The biochemistry of aromatic amines. II. The conversion of arylamines into arylsulphamic acids and arylamine-N-glucosiduronic acids.
E. Boyland
,
D. Manson
,
S. Orr
Biochemical Journal
1957
Corpus ID: 33658460
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