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Arylamine N-Acetyltransferase

Known as: Acetyl-CoA Arylamine N-Acetyltransferase, Arylamine N Acetyltransferase, Acetyl-CoA:arylamine N-acetyltransferase 
An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also catalyze acetyl transfer between arylamines without… 
National Institutes of Health

Related topics

Related topics

14 relations
In BloodN-hydroxyarylamine O-acetyltransferaseNAT1 geneNAT2 gene

Narrower (2)

N-acetyltransferase 1NAT2 protein, human

Papers overview

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Highly Cited
2005
Highly Cited
2005
Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines.
The NATs (arylamine N-acetyltransferases) are a well documented family of enzymes found in both prokaryotes and eukaryotes. NATs… 
Review
2003
Review
2003
Arylamine N-acetyltransferases: a pharmacogenomic approach to drug metabolism and endogenous function.
The arylamine N-acetyltransferases (NATs) are a unique family of enzymes that catalyse the transfer of an acetyl group from… 
2002
2002
Berberine Inhibited Arylamine N-Acetyltransferase Activity and Gene Expression and DNA Adduct Formation in Human Malignant Astrocytoma (G9T/VGH) and Brain Glioblastoma Multiforms (GBM 8401) Cells
Studies have demonstrated that berberine exhibits the antineoplastic action in rat model. Rat glial tumor cells also have been… 
2001
2001
Variation in enzymes of arylamine procarcinogen biotransformation among bladder cancer patients and control subjects.
Arylamines such as 2-naphthylamine and 4-aminobiphenyl are suspected human bladder procarcinogens that require bioactivation to… 
1991
1991
Functionalized membrane supports for covalent protein microsequence analysis.
1986
1986
N-hydroxyarylamine O-acetyltransferase in hamster liver: identity with arylhydroxamic acid N,O-acetyltransferase and arylamine N-acetyltransferase.
N-Hydroxyarylamine O-acetyltransferase, arylhydroxamic acid N,O-acetyltransferase, and arylamine N-acetyltransferase in hamster… 
Highly Cited
1985
Highly Cited
1985
DNA adducts formed from the probable proximate carcinogen, N-hydroxy-3,2' -dimethyl-4-aminobiphenyl, by acid catalysis or S-acetyl coenzyme A-dependent enzymatic esterification.
The arylamine carcinogen 3,2'-dimethyl-4-aminobiphenyl (DMABP) has been proposed to be metabolically activated to DNA-binding… 
1985
1985
Acetyl coenzyme A-dependent binding of carcinogenic and mutagenic dinitropyrenes to DNA.
Dinitropyrenes are mutagenic and carcinogenic environmental pollutants found in diesel emissions and urban air particulates. In… 
1983
1983
Purification and physical-chemical properties of acetyl-CoA:arylamine N-acetyltransferase from pigeon liver.
Highly Cited
1957
Highly Cited
1957
The biochemistry of aromatic amines. II. The conversion of arylamines into arylsulphamic acids and arylamine-N-glucosiduronic acids.
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