NAT2 gene

Known as: ARYLAMIDE ACETYLASE 2, N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) Gene, NAT-2 
This gene plays a role in both the activation and deactivation of xenobiotics.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2018
010203019882018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Associations between bladder cancer risk and NAT2 and GSTM1 polymorphisms have emerged as some of the most consistent findings in… (More)
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2009
2009
Methods: NAT2 genotyping of 201 subjects was carried out by PCR-restriction fragment length polymorphism (PCR-RFLP) analysis and… (More)
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Highly Cited
2008
Highly Cited
2008
Defined mutations in the mitochondrial ADP/ATP carrier (AAC) are associated with certain types of progressive external… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Many reported associations between common genetic polymorphisms and complex diseases have not been confirmed in… (More)
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Highly Cited
2003
Highly Cited
2003
AIMS The goal of this study was to determine the frequencies of important allelic variants in the TPMT, NAT2, GST, SULT1A1 and… (More)
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Highly Cited
1995
Highly Cited
1995
The polymorphic arylamine N-acetyltransferase (NAT2; EC 2.3.1.5) is supposed to be a susceptibility factor for several drug side… (More)
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1995
1995
Human polymorphic N-acetyltransferase (NAT2) catalyzes the N-acetylation of arylamine carcinogens and the metabolic activation of… (More)
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Highly Cited
1993
Highly Cited
1993
Carcinogenic arylamines are acetylated by the hepatic N-acetyltransferase. This enzyme is polymorphic in humans and in some… (More)
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Highly Cited
1993
Highly Cited
1993
A genetic polymorphism at the NAT2 gene locus, encoding for polymorphic N-acetyltransferase (NAT2), segregates individuals into… (More)
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1988
1988
Genetic and biochemical analysis of Saccharomyces cerevisiae containing a disruption of the nuclear gene (AAC1) encoding the… (More)
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