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NAT2 protein, human

Known as: N-acetyltransferase 2, human, N-Acetyltransferase, N-acetyltransferase 2 (arylamine N-acetyltransferase), human 
Arylamine N-acetyltransferase 2 (290 aa, ~34 kDa) is encoded by the human NAT2 gene. This protein plays a role in xenobiotic metabolism.
National Institutes of Health

Related topics

Related topics

7 relations
AANAT geneAcetylationEnzyme GeneMetabolic Detoxication, Drug

Broader (2)

Arylalkylamine N-AcetyltransferaseArylamine N-Acetyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Arylamine N-acetyltransferase 2 gene polymorphism in an Algerian population
Abstract Background: The arylamine N-acetyltransferase 2 (NAT2) is a key enzyme in the biotransformation of xenobiotics. NAT2… 
2016
2016
Helix handedness inversion in arylamide foldamers: elucidation and free energy profile of a hopping mechanism.
We report the first atomistic level description of the handedness inversion mechanism for helical arylamide foldamers. The key… 
2016
2016
Perinephric adipose tissue thickness in relation to blood pressure, plasma apelin and C-reactive protein levels in obese adolescents.
BACKGROUND Visceral adiposity plays an important role in the pathogenesis of obesity related hypertension. Measurement of… 
2014
2014
Genetic variation in aryl N-acetyltransferase results in significant differences in the pharmacokinetic and safety profiles of amifampridine (3,4-diaminopyridine) phosphate
The clinical use of amifampridine phosphate for neuromuscular junction disorders is increasing. The metabolism of amifampridine… 
2009
2009
Effect of respiration on the radiation dose distribution within target volume in radiotherapy
Objective: To evaluate the influence of respiration on the radiation dose distribution within target volume in radiotherapy with… 
2008
2008
Arylamide foldamers: A proteomimetic approach to disrupting protein -protein interactions
1997
1997
Study of the role of the highly conserved residues Arg9 and Arg64 in the catalytic function of human N-acetyltransferases NAT1 and NAT2 by site-directed mutagenesis.
The arylamine N-acetyltransferases (NATs) NAT1 and NAT2 are responsible for the biotransformation of many arylamine and… 
1996
1996
Development and validation of a patient needs assessment tool (PNAT) for oncology clinicians.
The Patient Needs Assessment Tool (PNAT) is an interviewer-rated scale that may be completed through a simple structured… 
Highly Cited
1995
Highly Cited
1995
Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium.
Heterocyclic aromatic amines formed during the cooking of meat and meat-derived products can be activated to reactive metabolites… 
1995
1995
Melatonin biosynthesis in photoreceptor-enriched chick retinal cell cultures: role of cyclic amp in the K+-evoked, ca2+ -dependent induction of serotonin n-acetyltransferase activity
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