NAT2 protein, human

Known as: N-acetyltransferase 2, human, N-Acetyltransferase, N-acetyltransferase 2 (arylamine N-acetyltransferase), human 
Arylamine N-acetyltransferase 2 (290 aa, ~34 kDa) is encoded by the human NAT2 gene. This protein plays a role in xenobiotic metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2017
0204019722017

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Highly Cited
2005
Highly Cited
2005
BACKGROUND Many reported associations between common genetic polymorphisms and complex diseases have not been confirmed in… (More)
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Highly Cited
2004
Highly Cited
2004
Tobacco smoking and occupation are major risk factors of bladder cancer via exposure to polycyclic aromatic hydrocarbons (PAHs… (More)
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Highly Cited
2002
Highly Cited
2002
Susceptibility to colorectal cancer, one of the most common forms of cancer in the Western world, has been associated with… (More)
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Highly Cited
2001
Highly Cited
2001
Serotonin N-acetyltransferase (AANAT) controls the daily rhythm in melatonin synthesis. When isolated from tissue, AANAT… (More)
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Highly Cited
1996
Highly Cited
1996
Foreign compound-metabolizing enzymes may modify the risk of chemically induced cancer. We wanted to examine enzymes with… (More)
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Highly Cited
1995
Highly Cited
1995
The metabolic activation and detoxification pathways associated with the carcinogenic aromatic amines provide an extraordinary… (More)
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Highly Cited
1995
Highly Cited
1995
The polymorphic arylamine N-acetyltransferase (NAT2; EC 2.3.1.5) is supposed to be a susceptibility factor for several drug side… (More)
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Highly Cited
1993
Highly Cited
1993
A genetic polymorphism at the NAT2 gene locus, encoding for polymorphic N-acetyltransferase (NAT2), segregates individuals into… (More)
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Highly Cited
1992
Highly Cited
1992
The wide variations in urinary bladder and colo-rectal cancer incidence in humans have been attributed in part to metabolic… (More)
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Highly Cited
1990
Highly Cited
1990
N-Acetylation by hepatic arylamine N-acetyltransferase (NAT, EC 2.3.1.5) is a major route in the metabolism and detoxification of… (More)
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