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Adenylate Cyclase

Known as: adenylylcyclase, Cyclases, Adenylyl, Adenylyl Cyclase 
Enzymes of the lyase class that catalyze the formation of CYCLIC AMP and pyrophosphate from ATP.
National Institutes of Health

Papers overview

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Review
1998
Review
1998
The diverse physiological actions of dopamine are mediated by at least five distinct G protein-coupled receptor subtypes. Two D1… Expand
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Highly Cited
1994
Highly Cited
1994
Estrogenic hormones, believed to exert most of their effects via the direct interaction of their receptors with chromatin, are… Expand
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Highly Cited
1989
Highly Cited
1989
A novel neuropeptide which stimulates adenylate cyclase in rat anterior pituitary cell cultures was isolated from ovine… Expand
Highly Cited
1982
Highly Cited
1982
  • S. Leppla
  • Proceedings of the National Academy of Sciences…
  • 1982
  • Corpus ID: 20307576
Anthrax toxin is composed of three proteins: protective antigen (PA), lethal factor (LF), and edema factor (EF). These proteins… Expand
Highly Cited
1982
Highly Cited
1982
  • T. Katada, M. Ui
  • Proceedings of the National Academy of Sciences…
  • 1982
  • Corpus ID: 33285877
GTP and isoproterenol activation of adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] in washed membranes… Expand
Highly Cited
1981
Highly Cited
1981
The diterpene, forskolin [half-maximal effective concentration (EC50), 5-10 microM] activates adenylate cyclase [ATP… Expand
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Highly Cited
1978
Highly Cited
1978
Treatment of pigeon erythrocyte membranes with cholera toxin and NAD(+) enhanced the GTP stimulation and suppressed the F… Expand
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Highly Cited
1978
Highly Cited
1978
  • D. Gill, R. Meren
  • Proceedings of the National Academy of Sciences…
  • 1978
  • Corpus ID: 25453003
In the presence of ATP and a cytosolic factor, cholera toxin fragment A1 catalyzes the transfer of ADP-ribose from NAD to a… Expand
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Highly Cited
1975
Highly Cited
1975
Narcotics affect adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] in two opposing ways, both mediated by the… Expand
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Highly Cited
1974
Highly Cited
1974
Abstract A highly sensitive adenylate cyclase assay method has been developed which employs sequential chromatography on columns… Expand