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Adenylate Cyclase

Known as: adenylylcyclase, Cyclases, Adenylyl, Adenylyl Cyclase 
Enzymes of the lyase class that catalyze the formation of CYCLIC AMP and pyrophosphate from ATP.
National Institutes of Health

Related topics

Related topics

21 relations
Adenosine MonophosphateCyclic AMPIn BloodProcess of secretion

Narrower (10)

Adenylyl Cyclase 9PsiP protein, Zea maysadenylate cyclase 3adenylate cyclase 9

Broader (2)

LyasePhosphorus-Oxygen Lyases

Papers overview

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Highly Cited
2000
Highly Cited
2000
Identification and Biological Activity of the Active Metabolite of Clopidogrel
Summary Like ticlopidine, the ADP receptor antagonist clopidogrel is inactive in vitro and must be administered i.v. or orally to… 
Highly Cited
1997
Highly Cited
1997
The adenylate cyclase gene MAC1 of Magnaporthe grisea controls appressorium formation and other aspects of growth and development.
Magnaporthe grisea, the causal agent of rice blast disease, differentiates a specialized infection structure called an… 
Highly Cited
1997
Highly Cited
1997
Cannabinoid receptors CB1 and CB2: a characterization of expression and adenylate cyclase modulation within the immune system.
Cannabinoid receptor (CB) expression was characterized in immunological cell and tissue preparations. Northern analysis revealed… 
Highly Cited
1994
Highly Cited
1994
ORL1, a novel member of the opioid receptor family
Highly Cited
1993
Highly Cited
1993
A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.
Highly Cited
1989
Highly Cited
1989
Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure.
Complementary DNA's that encode an adenylyl cyclase were isolated from a bovine brain library. Most of the deduced amino acid… 
Highly Cited
1982
Highly Cited
1982
Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts.
To identify the role of the myocardial beta-adrenergic pathway in congestive heart failure, we examined beta-adrenergic-receptor… 
Highly Cited
1982
Highly Cited
1982
Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.
Activation of the purified guanine nucleotide-binding regulatory component (G/F) of adenylate cyclase by F- requires the presence… 
Highly Cited
1975
Highly Cited
1975
Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance.
Narcotics affect adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] in two opposing ways, both mediated by the… 
Highly Cited
1968
Highly Cited
1968
A simple, sensitive method for the assay of adenyl cyclase.
A simple method for the amay of adenyl cyclase in tissue homogenates is described that uses either α-P82-, C14-or H3-labeled… 
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