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Adenylate Cyclase

Known as: adenylylcyclase, Cyclases, Adenylyl, Adenylyl Cyclase 
Enzymes of the lyase class that catalyze the formation of CYCLIC AMP and pyrophosphate from ATP.
National Institutes of Health

Related topics

Related topics

21 relations
Adenosine MonophosphateCyclic AMPIn BloodProcess of secretion

Narrower (10)

Adenylyl Cyclase 9PsiP protein, Zea maysadenylate cyclase 3adenylate cyclase 9

Broader (2)

LyasePhosphorus-Oxygen Lyases

Papers overview

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Highly Cited
1985
Highly Cited
1985
Coupling of the guanine nucleotide regulatory protein to chemotactic peptide receptors in neutrophil membranes and its uncoupling by islet-activating protein, pertussis toxin. A possible role of the…
Highly Cited
1985
Highly Cited
1985
Modulation of adenylate cyclase of human platelets by phorbol ester. Impairment of the hormone-sensitive inhibitory pathway.
The influence of the phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA), a direct activator of the Ca2+-activated… 
Highly Cited
1983
Highly Cited
1983
The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin).
Highly Cited
1983
Highly Cited
1983
Glucose Insensitivity and Amino-acid Hypersensitivity of Insulin Release in Rats with Non-insulin-dependent Diabetes: A Study with the Perfused Pancreas
Non-insulin-dependent diabetes (NIDDM) was obtained in adult rats following a neonatal streptozotocin injection. Rats with NIDDM… 
Highly Cited
1981
Highly Cited
1981
Molecular mechanisms involved in α-adrenergic responses
Highly Cited
1977
Highly Cited
1977
Cyclic adenosine 3',5'-monophosphate and prostacyclin inhibit membrane phospholipase activity in platelets.
Highly Cited
1977
Highly Cited
1977
Modulator binding protein. Bovine brain protein exhibiting the Ca2+-dependent association with the protein modulator of cyclic nucleotide phosphodiesterase.
Highly Cited
1976
Highly Cited
1976
Adenylyl cyclase activities in ovarian tissues. I. Homogenization and conditions of assay in graafian follicles and corpora lutea of rabbits, rats, and pigs: regulation by ATP, and some comparative…
Responsiveness of ovarian adenylyl cyclases to luteinizing hormone (LH), found to be 5 to 10-fold in cell-free preparations under… 
Highly Cited
1971
Highly Cited
1971
The biological significance of the prostaglandins.
Highly Cited
1970
Highly Cited
1970
Hormone-Sensitive Adenyl Cyclase: Cytochemical Localization in Rat Liver
An electron microscopic procedure has been developed, using rat liver, for the localization of hormone-sensitive adenyl cyclase… 
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