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Cyclic AMP

Known as: Adenosine Cyclic 3,5 Monophosphate, cAMP, Adenosine Cyclic 3',5'-Monophosphate 
A second messenger molecule comprised of an adenine ribonucleotide bearing a phosphate group bound to the oxygen molecules at the 3' and 5' positions… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The detection of pathogens through nucleic acid sensors is a defining principle of innate immunity. RNA-sensing and DNA-sensing… Expand
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Review
2018
Review
2018
Phosphodiesterase-4 (PDE4), mainly present in immune cells, epithelial cells, and brain cells, manifests as an intracellular non… Expand
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Highly Cited
2004
Highly Cited
2004
NF‐κB is responsible for upregulating gene products that control cell survival. In this study, we demonstrate that SIRT1, a… Expand
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Highly Cited
2002
Highly Cited
2002
Myelin inhibitors, including MAG, are major impediments to CNS regeneration. However, CNS axons of DRGs regenerate if the… Expand
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Highly Cited
1998
Highly Cited
1998
Rap1 is a small, Ras-like GTPase that was first identified as a protein that could suppress the oncogenic transformation of cells… Expand
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Highly Cited
1995
Highly Cited
1995
To investigate whether polymorphic forms of the human dopamine D4 receptor have different functional characteristics, we have… Expand
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Highly Cited
1991
Highly Cited
1991
CYCLIC AMP acts as a second messenger in the modulation of several ion channels1–9 that are typically controlled by a… Expand
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Highly Cited
1990
Highly Cited
1990
A newly synthesized isoquinolinesulfonamide, H-89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinoline-sulfonamide), was shown to… Expand
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Highly Cited
1989
Highly Cited
1989
In this paper, we demonstrate that phosphorylation of CREB at Ser-133 is induced 6-fold in vivo, following treatment of PC12… Expand
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Highly Cited
1982
Highly Cited
1982
  • S. Leppla
  • Proceedings of the National Academy of Sciences…
  • 1982
  • Corpus ID: 20307576
Anthrax toxin is composed of three proteins: protective antigen (PA), lethal factor (LF), and edema factor (EF). These proteins… Expand
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