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8-cyclopentyl-1,3-dimethylxanthine

Known as: 8-CPDMX, 8-cyclopentyltheophylline 
 
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
Extracellular adenosine significantly reduced cell viability in a dose (0.1-20mM)- and treatment time (24-72h)-dependent manner… Expand
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Highly Cited
2003
Highly Cited
2003
Adenosine is a neuromodulator in the nervous system and it has recently been observed that pharmacological blockade or gene… Expand
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Highly Cited
2003
Highly Cited
2003
At the calyx of Held synapse in brainstem slices of 5‐ to 7‐day‐old (P5–7) rats, adenosine, or the type 1 adenosine (A1) receptor… Expand
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Highly Cited
2003
Highly Cited
2003
Sleep deprivation (SD) increases extracellular adenosine levels in the basal forebrain, and pharmacological manipulations that… Expand
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Highly Cited
1993
Highly Cited
1993
Adenosine is a potent inhibitory modulator of synaptic transmission in the CNS, but its role in normal physiological function is… Expand
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Highly Cited
1991
Highly Cited
1991
Abstract: In rat hippocampal synaptosomes, adenosine decreased the K+ (15 mM) or the kainate (1 mM) evoked release of glutamate… Expand
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Highly Cited
1991
Highly Cited
1991
The effects of adenosine on inhibitory synaptic transmission in area CA1 were examined using the rat hippocampal slice… Expand
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Highly Cited
1989
Highly Cited
1989
Characterization of the adenosine A2 receptor has been limited due to the lack of available ligands which have high affinity and… Expand
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Highly Cited
1989
Highly Cited
1989
Adenosine is a neuromodulator with multiple actions upon the physiology and biochemistry of the brain. Although the receptors… Expand
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Highly Cited
1986
Highly Cited
1986
[3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuronamide) is known to bind to both the A1 and A2 subtypes of… Expand
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