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8-cyclopentyl-1,3-dimethylxanthine

Known as: 8-CPDMX, 8-cyclopentyltheophylline 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

PD 116,600

Broader (2)

Purinergic P1 Receptor AntagonistsTheophylline
analogs & derivatives

Papers overview

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Highly Cited
2003
Highly Cited
2003
Neuroprotection by caffeine and adenosine A2A receptor blockade of β‐amyloid neurotoxicity
Adenosine is a neuromodulator in the nervous system and it has recently been observed that pharmacological blockade or gene… 
Highly Cited
1998
Highly Cited
1998
Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat
Highly Cited
1996
Highly Cited
1996
Adenosine A1 and A2 receptors modulate extracellular dopamine levels in rat striatum
Highly Cited
1995
Highly Cited
1995
Adenosine Receptors Modulate [Ca2+]i in Hippocampal Astrocytes In Situ
Abstract: Cultured astroglia express both adenosine and ATP purinergic receptors that are coupled to increases in intracellular… 
Highly Cited
1994
Highly Cited
1994
Propentofylline and Other Adenosine Transport Inhibitors Increase the Efflux of Adenosine Following Electrical or Metabolic Stimulation of Rat Hippocampal Slices
Abstract: Propentofylline is a novel neuroprotective agent that has been shown to act as an adenosine transport inhibitor as well… 
Highly Cited
1991
Highly Cited
1991
Adenosine depresses excitatory but not fast inhibitory synaptic transmission in area CA1 of the rat hippocampus
Highly Cited
1991
Highly Cited
1991
Adenosine and Glutamate Modulate Each Other's Release from Rat Hippocampal Synaptosomes
Abstract: In rat hippocampal synaptosomes, adenosine decreased the K+ (15 mM) or the kainate (1 mM) evoked release of glutamate… 
Highly Cited
1991
Highly Cited
1991
Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.
The locomotor effects in mice of selective A1 and A2 adenosine agonists, antagonists and combinations of agonists were… 
Highly Cited
1989
Highly Cited
1989
[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.
Characterization of the adenosine A2 receptor has been limited due to the lack of available ligands which have high affinity and… 
Highly Cited
1989
Highly Cited
1989
Role of endogenous adenosine in recurrent generalized seizures
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