International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.
- B. Fredholm, A. IJzerman, K. Jacobson, K. Klotz, J. Linden
- BiologyPharmacological Reviews
- 1 December 2001
Experiments with receptor antagonists and mice with targeted disruption of adenosine A(1), A(2A), and A(3) expression reveal roles for these receptors under physiological and particularly pathophysiological conditions.
International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors: From Molecular Mechanisms and Pathophysiology to Therapy
There have been many advances in our knowledge about different aspects of P2Y receptor signaling since the last review published by our International Union of Pharmacology subcommittee. More receptor…
Adenosine receptors as therapeutic targets
Recent advances in the understanding of the roles of the various adenosine receptor subtypes, and in the development of selective and potent ligands, have brought the goal of therapeutic application of adenosines receptor modulators considerably closer.
Structure of an Agonist-Bound Human A2A Adenosine Receptor
The molecule UK-432097 is defined as a “conformationally selective agonist” capable of receptor stabilization in a specific active-state configuration and sheds light on G protein–coupled receptor activation.
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update
- B. Fredholm, A. IJzerman, K. Jacobson, J. Linden, C. Müller
- Biology, MedicinePharmacological Reviews
- 1 March 2011
In the 10 years since our previous International Union of Basic and Clinical Pharmacology report on the nomenclature and classification of adenosine receptors, no developments have led to major…
UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis
The P2Y6 receptor is upregulated when neurons are damaged, and could function as a sensor for phagocytosis by sensing diffusible UDP signals, which is a previously unknown pathophysiological function of P2 receptors in microglia.
Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family.
Hematoxylin and eosin staining of tissue and cell sections.
This protocol describes H&E staining of tissue and cell sections and discloses abundant structural information, with specific functional implications of hematoxylin staining.
Purine and pyrimidine (P2) receptors as drug targets.
Adenosine A3 receptors: novel ligands and paradoxical effects.
- K. Jacobson
- BiologyTIPS - Trends in Pharmacological Sciences
- 1 May 1998