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Theophylline

Known as: 1,3-dimethyl-7H-purine-2,6-dione, 1,3-dimethylxanthine, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione 
A natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
RATIONALE Patients with chronic obstructive pulmonary disease (COPD) show a poor response to corticosteroids. This has been… Expand
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Highly Cited
2006
Highly Cited
2006
The crystal form adopted by the respiratory drug theophylline was modified using a crystal engineering strategy in order to… Expand
Highly Cited
2004
Highly Cited
2004
Chronic obstructive pulmonary disease (COPD) is a common chronic inflammatory disease of the lungs with little or no response to… Expand
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Highly Cited
2002
Highly Cited
2002
The molecular mechanism for the anti-inflammatory action of theophylline is currently unknown, but low-dose theophylline is an… Expand
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Review
2001
Review
2001
The chemical composition of St. John's wort has been well‐studied. Documented pharmacological activities, including… Expand
Highly Cited
1992
Highly Cited
1992
Tea is grown in about 30 countries but is consumed worldwide, although at greatly varying levels. It is the most widely consumed… Expand
Review
1988
Review
1988
Ciprofloxacin is one of a new generation of fluorinated quinolones structurally related to nalidixic acid. The primary mechanism… Expand
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Highly Cited
1978
Highly Cited
1978
Volume 1: immunology biology of eosinophils pathophysiology of allergic inflammation physiology pharmacology principles of… Expand
Review
1978
Review
1978
  • R. Ogilvie
  • Clinical pharmacokinetics
  • 1978
  • Corpus ID: 30411832
SummaryKnowledge acquired of the kinetic disposition and effects of theophylline over the past 8 years has increased the clinical… Expand
Highly Cited
1973
Highly Cited
1973
Abstract Physiologic responses to intravenously administered theophylline were determined in nine hospitalized asthmatic subjects… Expand