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Purinergic P1 Receptor Antagonists

Known as: Adenosine Receptor Antagonists, P1 Purinoceptor Antagonists, Receptor Antagonists, Adenosine 
Compounds that bind to and block the stimulation of PURINERGIC P1 RECEPTORS.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
A 2A adenosine receptor antagonists usually have bi- or tricyclic N aromatic systems with varying substitution patterns to… Expand
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Review
2006
Review
2006
Ever since the discovery of the hypotensive and bradycardiac effects of adenosine, adenosine receptors continue to represent… Expand
Highly Cited
2005
Highly Cited
2005
Memory loss in humans begins early in adult life and progresses thereafter. It is not known whether these losses reflect the… Expand
Highly Cited
2004
Highly Cited
2004
Caffeine, an adenosine A1, A2A, and A2B receptor antagonist, is frequently used as an adjuvant analgesic in combination with… Expand
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE Weekly low-dose methotrexate (MTX) remains the mainstay of second-line therapy for rheumatoid arthritis (RA). We have… Expand
Highly Cited
1999
Highly Cited
1999
3,5-Diacyl-2,4-dialkyl-6-phenylpyridine derivatives have been found to be selective antagonists at both human and rat A3… Expand
Highly Cited
1999
Highly Cited
1999
This study determined the levels of adenosine in the renal medullary interstitium using microdialysis and fluorescence HPLC… Expand
Highly Cited
1998
Highly Cited
1998
New A2A adenosine receptor antagonists in the series of pyrazolo[4, 3-e]-1,2,4-triazolo[1,5-c]pyrimidines, bearing oxygenated… Expand
Highly Cited
1997
Highly Cited
1997
The effects of nonselective (theophylline), A1-(DPCPX) or A2A-selective (SCH 58261) adenosine receptor antagonists administered… Expand
Highly Cited
1995
Highly Cited
1995
Cerebral ischemia of 5 min duration was induced in unanesthetized Mongolian gerbils by bilateral occlusion of the carotid… Expand