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Purinergic P1 Receptor Antagonists

Known as: Adenosine Receptor Antagonists, P1 Purinoceptor Antagonists, Receptor Antagonists, Adenosine 
Compounds that bind to and block the stimulation of PURINERGIC P1 RECEPTORS.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
A 2A adenosine receptor antagonists usually have bi- or tricyclic N aromatic systems with varying substitution patterns to… Expand
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Highly Cited
2005
Highly Cited
2005
Memory loss in humans begins early in adult life and progresses thereafter. It is not known whether these losses reflect the… Expand
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Highly Cited
2004
Highly Cited
2004
Caffeine, an adenosine A1, A2A, and A2B receptor antagonist, is frequently used as an adjuvant analgesic in combination with… Expand
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE Weekly low-dose methotrexate (MTX) remains the mainstay of second-line therapy for rheumatoid arthritis (RA). We have… Expand
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Highly Cited
1999
Highly Cited
1999
3,5-Diacyl-2,4-dialkyl-6-phenylpyridine derivatives have been found to be selective antagonists at both human and rat A3… Expand
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Highly Cited
1999
Highly Cited
1999
This study determined the levels of adenosine in the renal medullary interstitium using microdialysis and fluorescence HPLC… Expand
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Highly Cited
1998
Highly Cited
1998
Cell motility is an essential component of tumor progression and metastasis. A number of factors, both autocrine and paracrine… Expand
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Highly Cited
1997
Highly Cited
1997
The effects of nonselective (theophylline), A1-(DPCPX) or A2A-selective (SCH 58261) adenosine receptor antagonists administered… Expand
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Highly Cited
1995
Highly Cited
1995
Cerebral ischemia of 5 min duration was induced in unanesthetized Mongolian gerbils by bilateral occlusion of the carotid… Expand
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Highly Cited
1995
Highly Cited
1995
Ischemia-reperfusion (I-R) injury of the lung occurs after lung transplantation, pulmonary thromboembolectomy, or cardiopulmonary… Expand
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