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Purinergic P1 Receptor Antagonists
Known as:
Adenosine Receptor Antagonists
, P1 Purinoceptor Antagonists
, Receptor Antagonists, Adenosine
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Compounds that bind to and block the stimulation of PURINERGIC P1 RECEPTORS.
National Institutes of Health
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18 relations
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
A1 adenosine receptor antagonists, agonists, and allosteric enhancers.
W. Kiesman
,
E. Elzein
,
J. Zablocki
Handbook of Experimental Pharmacology
2009
Corpus ID: 24341869
Intense efforts of many pharmaceutical companies and academicians in the A(1) adenosine receptor (AR) field have led to the…
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Review
2006
Review
2006
Progress in the pursuit of therapeutic adenosine receptor antagonists
S. Moro
,
Zhang-Guo Gao
,
K. Jacobson
,
G. Spalluto
Medicinal research reviews (Print)
2006
Corpus ID: 13758102
Ever since the discovery of the hypotensive and bradycardiac effects of adenosine, adenosine receptors continue to represent…
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Highly Cited
2005
Highly Cited
2005
Long-Term Potentiation Is Impaired in Middle-Aged Rats: Regional Specificity and Reversal by Adenosine Receptor Antagonists
Christopher Rex
,
E. Kramár
,
L. Colgin
,
B. Lin
,
C. Gall
,
G. Lynch
Journal of Neuroscience
2005
Corpus ID: 17698595
Memory loss in humans begins early in adult life and progresses thereafter. It is not known whether these losses reflect the…
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Highly Cited
2004
Highly Cited
2004
Antinociceptive Effects of Novel A2B Adenosine Receptor Antagonists
O. Abo-Salem
,
A. Hayallah
,
A. Bilkei-Gorzo
,
B. Filipek
,
A. Zimmer
,
C. Müller
Journal of Pharmacology and Experimental…
2004
Corpus ID: 7843340
Caffeine, an adenosine A1, A2A, and A2B receptor antagonist, is frequently used as an adjuvant analgesic in combination with…
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Highly Cited
2000
Highly Cited
2000
Reversal of the antiinflammatory effects of methotrexate by the nonselective adenosine receptor antagonists theophylline and caffeine: evidence that the antiinflammatory effects of methotrexate are…
M. Montesinos
,
Josephine S. Yap
,
Avani Desai
,
Inmaculada Posadas
,
Christine T. McCrary
,
B. Cronstein
Arthritis & Rheumatism
2000
Corpus ID: 32498088
OBJECTIVE Weekly low-dose methotrexate (MTX) remains the mainstay of second-line therapy for rheumatoid arthritis (RA). We have…
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Highly Cited
1999
Highly Cited
1999
Synthesis, CoMFA analysis, and receptor docking of 3,5-diacyl-2, 4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.
An-Hu Li
,
Stefano Moro
,
Nancy Forsyth
,
N. Melman
,
X. Ji
,
Kenneth A Jacobson
Journal of Medicinal Chemistry
1999
Corpus ID: 24520174
3,5-Diacyl-2,4-dialkyl-6-phenylpyridine derivatives have been found to be selective antagonists at both human and rat A3…
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Highly Cited
1999
Highly Cited
1999
Role of renal medullary adenosine in the control of blood flow and sodium excretion.
A. Zou
,
K. Nithipatikom
,
Pin-Lan Li
,
A. Cowley
American Journal of Physiology. Regulatory…
1999
Corpus ID: 4470839
This study determined the levels of adenosine in the renal medullary interstitium using microdialysis and fluorescence HPLC…
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Highly Cited
1997
Highly Cited
1997
Neonatal cerebral hypoxia-ischemia: The effect of adenosine receptor antagonists
E. Bona
,
U. Ådén
,
E. Gilland
,
B. Fredholm
,
H. Hagberg
Neuropharmacology
1997
Corpus ID: 34692111
Highly Cited
1995
Highly Cited
1995
The effects of selective A1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil
J. Phillis
Brain Research
1995
Corpus ID: 37290179
Highly Cited
1995
Highly Cited
1995
A1 adenosine receptor antagonists block ischemia-reperfusion injury of the lung.
Constance F. Neely
,
I. Keith
American Journal of Physiology
1995
Corpus ID: 7826979
Ischemia-reperfusion (I-R) injury of the lung occurs after lung transplantation, pulmonary thromboembolectomy, or cardiopulmonary…
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