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Purinergic P1 Receptor Antagonists

Known as: Adenosine Receptor Antagonists, P1 Purinoceptor Antagonists, Receptor Antagonists, Adenosine 
Compounds that bind to and block the stimulation of PURINERGIC P1 RECEPTORS.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
A 2A adenosine receptor antagonists usually have bi- or tricyclic N aromatic systems with varying substitution patterns to… 
Review
2006
Review
2006
Ever since the discovery of the hypotensive and bradycardiac effects of adenosine, adenosine receptors continue to represent… 
Highly Cited
2005
Highly Cited
2005
Memory loss in humans begins early in adult life and progresses thereafter. It is not known whether these losses reflect the… 
Highly Cited
2004
Highly Cited
2004
Caffeine, an adenosine A1, A2A, and A2B receptor antagonist, is frequently used as an adjuvant analgesic in combination with… 
Highly Cited
2000
Highly Cited
2000
OBJECTIVE Weekly low-dose methotrexate (MTX) remains the mainstay of second-line therapy for rheumatoid arthritis (RA). We have… 
Highly Cited
1999
Highly Cited
1999
3,5-Diacyl-2,4-dialkyl-6-phenylpyridine derivatives have been found to be selective antagonists at both human and rat A3… 
Highly Cited
1998
Highly Cited
1998
Cell motility is an essential component of tumor progression and metastasis. A number of factors, both autocrine and paracrine…