5-hydroxytryptamine uptake

Known as: 5HT uptake, serotonin import, serotonin uptake 
The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine… (More)

Topic mentions per year

Topic mentions per year

1960-2017
05010019602017

Papers overview

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Highly Cited
2000
Highly Cited
2000
Hypoxia is a well-recognized stimulus for pulmonary blood vessel remodeling and pulmonary hypertension development. One mechanism… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Genetic variation of the promoter for the serotonin transporter (5-HTT) gene has been associated with its functional… (More)
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Highly Cited
1999
Highly Cited
1999
The human serotonin transporter (5-HTT), encoded by a single gene on chromosome 17q11.2, is expressed in brain and blood cells. 5… (More)
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Highly Cited
1996
Highly Cited
1996
Transporter-facilitated uptake of serotonin (5-hydroxytryptamine or 5-HT) has been implicated in anxiety in humans and animal… (More)
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Highly Cited
1996
Highly Cited
1996
The serotonin transporter (5-HTT) is a candidate locus for aetiological involvement in affective disorders. Biochemical studies… (More)
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Highly Cited
1994
Highly Cited
1994
The gene encoding the human serotonin transporter (5-HTT) has been isolated and characterized. The human 5-HTT gene is composed… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Amitriptyline reduces the pain caused by peripheral-nerve disease, but treatment is often limited by side effects… (More)
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1990
1990
This study examined the [3H]5-HT-releasing properties of 3,4-methylenedioxymethamphetamine (MDMA) and related agents, all of… (More)
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Highly Cited
1987
Highly Cited
1987
Paroxetine was shown to be a potent (K i =1.1 nM) and specific inhibitor of [3H]-5-hydroxytryptamine (5-HT) uptake into rat… (More)
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1977
1977
1. On the basis of both in vitro and in vivo experiments fluvoxamine has been characterized as a potential anti-depressant drug… (More)
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