1,8-dinitropyrene

Known as: DINITROPYRENE, 1,8-, Pyrene, 1,8-dinitro- 
A synthetic, yellow crystalline solid that is insoluble in water and moderately soluble in toluene. It is not used for any commercial applications… (More)
National Institutes of Health

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Broader (3)

CarcinogensMutagensPyrenes

Papers overview

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2000
2000
Mutagenic activity of surface soil and quantification of 1,3-, 1,6-, and 1,8-dinitropyrene isomers in soil in Japan.
To clarify the mutagenic potential of nonagricultural surface soil in Japan, 110 soil samples were collected from five… (More)
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2000
2000
Synthesis and characterization of oligodeoxynucleotides containing the major DNA adducts formed by 1,6- and 1,8-dinitropyrene.
[reaction: see text] An efficient method for the synthesis of oligonucleotides containing a site-specific DNA adduct formed by… (More)
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Highly Cited
1996
Highly Cited
1996
Human cell mutagenicity of oxygenated, nitrated and unsubstituted polycyclic aromatic hydrocarbons associated with urban aerosols.
Polycyclic aromatic compounds (PAC) are ubiquitous pollutants in urban air that may pose risks to human health. In order to… (More)
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1995
1995
Erythrocyte-mediated toxification of 1,8-dinitropyrene: I. Reduction.
Nitroarenes are environmental contaminants produced during incomplete combustion processes. It has been reported that… (More)
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1990
1990
Inactivation of 1,3-, 1,6-, and 1,8-dinitropyrene by cytochrome P-450 enzymes in human and rat liver microsomes.
NADPH-fortified human liver microsomes were examined with regard to ability to detoxicate several chemicals that do not require… (More)
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1990
1990
Activation and detoxification of 1,8-dinitropyrene by mammalian hepatic fractions in the Salmonella mutagenicity assay.
1,8-Dinitropyrene (DNP) is a potent, direct-acting mutagen to Salmonella typhimurium TA98 due to activation by bacterial… (More)
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1986
1986
Structure of the c-Ki-ras gene in a rat fibrosarcoma induced by 1,8-dinitropyrene.
Restriction enzyme maps were made of the region around exons 1 and 2 of activated c-Ki-ras of a fibrosarcoma (1,8-DNP2) induced… (More)
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1985
1985
Absence of carcinogenicity of 1-nitropyrene, correction of previous results, and new demonstration of carcinogenicity of 1,6-dinitropyrene in rats.
1-Nitropyrene (1-NP), 1,6-dinitropyrene (1,6-DNP) and 1,8-dinitropyrene (1,8-DNP), which are potent mutagenic components of… (More)
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1984
1984
Metabolism of 1,8-dinitropyrene by Salmonella typhimurium.
Earlier work has shown that many nitroaromatic and nitroheterocyclic compounds are directly 'activated' to their ultimate… (More)
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1983
1983
The basis of the insensitivity of Salmonella typhimurium strain TA98/1,8-DNP6 to the mutagenic action of nitroarenes.
Salmonella typhimurium tester strain TA98/1,8-DNP6 is resistant to the mutagenicity of 1,8-dinitropyrene because it lacks an… (More)
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