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trans-4-methylcyclohexylamine

National Institutes of Health

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4-methylcyclohexylamine

Papers overview

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2015
2015
Structural insights into the novel inhibition mechanism of Trypanosoma cruzi spermidine synthase.
Trypanosoma cruzi causes Chagas disease, a severe disease affecting 8-10 million people in Latin America. While nifurtimox and… 
2011
2011
Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells
Polyamines spermidine and spermine are known to be required for mammalian cell proliferation and for embryonic development. Alpha… 
Review
2010
Review
2010
[Identification of novel molecules regulating differentiation and hormone secretion and clarification of their functional mechanisms in pancreatic endocrine cells].
In order to find novel bioactive molecules regulating differentiation and hormone secretion of pancreatic endocrine cells, the… 
2008
2008
Inhibition of Cell Growth by Combination of ƒ ¿-Difluoromethylornithine and an Inhibitor of Spermine Synthase 1
ylamine (APCHA) and trans-4-methylcyclohexylamine (4MCHA) were used as inhibitors of spermine and spermidine synthases… 
2006
2006
Inhibition of putrescine aminopropyltransferase influences rat liver regeneration.
A close relationship between rat liver regeneration and the concentration ratio of spermidine to spermine (spd:spm) was… 
Review
2006
Review
2006
[Regulation of polyamine and cancer].
  • K. Samejima
  • Yakugaku zasshi : Journal of the Pharmaceutical…
  • 2006
  • Corpus ID: 23217951
This review describes my work in the field of polyamine research for the last 35 years. My research started with developing the… 
1995
1995
Inhibition of cell growth by combination of alpha-difluoromethylornithine and an inhibitor of spermine synthase.
The inhibitory effect on cell growth of a combination of alpha-difluoromethylornithine (DFMO) and an inhibitor of aminopropyl… 
1995
1995
Antagonistic effect of N-(3-Aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons.
We previously found that spermine potently promotes the neuronal survival and regeneration of primary cultured brain neurons. N… 
1994
1994
N-(3-aminopropyl)-cyclohexylamine blocks facilitation by spermidine of N-methyl-DL-aspartate-induced seizure in mice in vivo.
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