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tetracenomycin
Known as:
1,4,4a,5,12,12a-hexahydro-4,4a,11,12a-tetrahydroxy-3,8-dimethoxy-9-methoxycarbonyl-10-methyl-1,5,12-trioxonaphthacene
National Institutes of Health
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Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Seco-Tetracenomycins from the Marine-Derived Actinomycete Saccharothrix sp. 10-10
B. Liu
,
Jiao Li
,
+7 authors
Maoluo Gan
Marine Drugs
2018
Corpus ID: 52312557
Six new tetracenomycin congeners, saccharothrixones E–I (1–5) and 13-de-O-methyltetracenomycin X (6), were isolated from the rare…
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2014
2014
[Identification of tetracenomycin X from a marine-derived Saccharothrix sp. guided by genes sequence analysis].
B. Liu
,
Yi Tan
,
+6 authors
Chun-ling Xiao
Yao xue xue bao = Acta pharmaceutica Sinica
2014
Corpus ID: 21242356
The crude extracts of the fermentation broth from a marine sediment-derived actinomycete strain, Saccharothrix sp. 10-10, showed…
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2010
2010
Hatomarubigin E, a biosynthetic intermediate of hatomarubigins C and a substrate of HrbU O-methyltransferase
T. Kawasaki
,
Y. Yamada
,
Tomoka Maruta
,
A. Maeda
,
Y. Hayakawa
Journal of antibiotics (Tokyo. )
2010
Corpus ID: 3251124
Hatomarubigin E, a biosynthetic intermediate of hatomarubigins C and a substrate of HrbU O -methyltransferase
2004
2004
The acyltransferase homologue from the initiation module of the R1128 polyketide synthase is an acyl-ACP thioesterase that edits acetyl primer units.
Yi Tang
,
A. Koppisch
,
C. Khosla
Biochemistry
2004
Corpus ID: 45527480
Type II polyketide synthases (PKSs) synthesize polyfunctional aromatic polyketides through iterative condensations of malonyl…
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2001
2001
Cloning, sequencing, and heterologous expression of the elmGHIJ genes involved in the biosynthesis of the polyketide antibiotic elloramycin from Streptomyces olivaceus Tü2353.
E. R. Rafanan
,
L. Le
,
L. Zhao
,
H. Decker
,
B. Shen
Journal of Natural Products
2001
Corpus ID: 41382765
Elloramycin A (1) belongs to a small family of naphthacenequinones characterized by a unique highly hydroxylated cyclohexenone…
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1999
1999
DnrD cyclase involved in the biosynthesis of doxorubicin: purification and characterization of the recombinant enzyme.
S. Kendrew
,
K. Katayama
,
E. Deutsch
,
K. Madduri
,
C. Hutchinson
Biochemistry
1999
Corpus ID: 21589875
Mutations in the Streptomyces peucetius dnrD gene block the ring cyclization leading from aklanonic acid methyl ester (AAME) to…
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1996
1996
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.
G. Blanco
,
H. Fu
,
C. Méndez
,
C. Khosla
,
J. Salas
Chemistry and Biology
1996
Corpus ID: 23237552
1995
1995
Functional analysis of putative beta-ketoacyl:acyl carrier protein synthase and acyltransferase active site motifs in a type II polyketide synthase of Streptomyces glaucescens
G. Meurer
,
C. Hutchinson
Journal of Bacteriology
1995
Corpus ID: 29356607
The significance of potential active site motifs for acyltransferase and beta-ketoacyl:acyl carrier protein synthase regions…
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1994
1994
Overproduction of the acyl carrier protein component of a type II polyketide synthase stimulates production of tetracenomycin biosynthetic intermediates in Streptomyces glaucescens.
H. Decker
,
R. Summers
,
C. Hutchinson
Journal of antibiotics (Tokyo. )
1994
Corpus ID: 33375160
The development of microorganisms with improved antibiotic production is an important goal in the commercialization of new…
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1992
1992
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis
Teresa J. Arrowsmith
,
F. Malpartida
,
D. Sherman
,
A. Birch
,
D. Hopwood
,
John A. Robinson
Molecular and General Genetics MGG
1992
Corpus ID: 25361357
SummaryCloned DNA encoding polyketide synthase (PKS) genes from one Streptomyces species was previously shown to serve as a…
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