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stress-activated protein kinase 1

Known as: SAPK1/JNK, SAPK/JNK, c-JUN N-Terminal Kinase 
A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with… 
National Institutes of Health

Related topics

Related topics

50 relations
ATM Signaling PathwayAdipocytokine Signaling PathwayAgrin PathwayApoptosis

Broader (1)

JNK Mitogen-Activated Protein Kinases

Narrower (1)

MAP3K8 protein, human

Papers overview

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Highly Cited
2003
Highly Cited
2003
Interleukin-1 beta and tumor necrosis factor-alpha induce MUC5AC overexpression through a mechanism involving ERK/p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial…
Mucin hypersecretion is commonly observed in many inflammatory diseases of the respiratory tract. MUC5AC is generally recognized… 
Highly Cited
2001
Highly Cited
2001
Cytoskeletal Changes Regulated by the PAK4 Serine/Threonine Kinase Are Mediated by LIM Kinase 1 and Cofilin*
PAK4 is the most recently identified member of the PAK family of serine/threonine kinases. PAK4 differs from other members of the… 
Highly Cited
2000
Highly Cited
2000
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7.
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to… 
Highly Cited
2000
Highly Cited
2000
Phosphorylation of Collapsin Response Mediator Protein-2 by Rho-kinase
We previously identified Rho-associated protein kinase (Rho-kinase) as a specific effector of Rho. In this study, we identified… 
Highly Cited
1999
Highly Cited
1999
Stress-activated Protein Kinase-2/p38 and a Rapamycin-sensitive Pathway Are Required for C2C12 Myogenesis*
The differentiation of C2C12 myoblasts to myotubes was found to be accompanied by a strong activation of p70 S6 kinase and the… 
Review
1998
Review
1998
Neurofilaments in health and disease.
Highly Cited
1997
Highly Cited
1997
Cell Cycle-dependent Expression and Spindle Pole Localization of a Novel Human Protein Kinase, Aik, Related to Aurora of Drosophila and Yeast Ipl1*
Mutations in Aurora of Drosophila and related Saccharomyces cerevisiae Ipl1 kinase are known to cause abnormal chromosome… 
Highly Cited
1992
Highly Cited
1992
Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression.
Recent studies have shown that there exists a family of protein kinases structurally and functionally related to the yeast cell… 
Highly Cited
1988
Highly Cited
1988
The nucleoplasmin nuclear location sequence is larger and more complex than that of SV-40 large T antigen
The carboxy-terminal tail of nucleoplasmin, which specifies entry into the cell nucleus, contains four short sequences that are… 
Highly Cited
1982
Highly Cited
1982
Sequence and structure of yeast phosphoglycerate kinase.
The structure of yeast phosphoglycerate kinase has been determined with data obtained from amino acid sequence, nucleotide… 
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