stress-activated protein kinase 1

Known as: SAPK1/JNK, SAPK/JNK, c-JUN N-Terminal Kinase 
A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The extracellular signal-regulated kinase (ERK)/MAPK (mitogen-activated protein kinase) cascade has been established as a potent… (More)
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Highly Cited
2006
Highly Cited
2006
The Snf1/AMP-activated protein kinase (AMPK) family is important for metabolic regulation and is highly conserved from yeast to… (More)
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Highly Cited
2004
Highly Cited
2004
Activation of the transcription factor cAMP response element-binding protein (CREB) by neurotrophins is believed to regulate the… (More)
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Highly Cited
2001
Highly Cited
2001
TRAF6 is a signal transducer that activates IκB kinase (IKK) and Jun amino-terminal kinase (JNK) in response to pro-inflammatory… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Protein kinase B (PKB), and the p70 and p90 ribosomal S6 kinases (p70 S6 kinase and p90 Rsk, respectively), are… (More)
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Highly Cited
1999
Highly Cited
1999
Extracellular signals regulate actin dynamics through small GTPases of the Rho/Rac/Cdc42 (p21) family. Here we show that p21… (More)
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Highly Cited
1999
Highly Cited
1999
The differentiation of C2C12 myoblasts to myotubes was found to be accompanied by a strong activation of p70 S6 kinase and the… (More)
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Highly Cited
1997
Highly Cited
1997
Vascular endothelial growth factor (VEGF) is a potent chemotactic agent for endothelial cells. Yet the signalling pathways that… (More)
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Highly Cited
1997
Highly Cited
1997
An increase in the intracellular calcium ion concentration ([Ca2+]i) controls a diverse range of cell functions, including… (More)
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Highly Cited
1992
Highly Cited
1992
A homology-based cDNA cloning approach was used to identify a widely expressed protein-tyrosine kinase designated as "focal… (More)
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