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ATM Signaling Pathway

The ataxia telangiectasia-mutated gene (ATM) encodes a protein kinase that acts as a tumor suppressor. ATM activation by ionizing radiation damage to… 
National Institutes of Health

Papers overview

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2016
2016
The purpose of this study was to evaluate the radiation-enhancing effect of sodium glycididazole, and the corresponding… 
Highly Cited
2009
Highly Cited
2009
Functional telomeres are required to maintain the replicative ability of cancer cells and represent putative targets for G… 
2009
2009
AbstractAim:The aim of this study was to investigate the mechanism of pseudolaric acid B (PLAB)-induced cell cycle arrest in… 
2006
2006
Activation of the ATM DNA damage response pathway is commonly observed in avariety of early-stage neoplasias. It has been… 
Highly Cited
2006
Highly Cited
2006
The phytochemical indole‐3‐carbinol (I3C), from cruciferous vegetables such as broccoli, has been shown to elicit a potent anti… 
Highly Cited
2004
Highly Cited
2004
The p53 tumor suppressor protein is phosphorylated and activated by several DNA damage-inducible kinases, such as ATM, and is a… 
Highly Cited
2001
Highly Cited
2001
The Nbs1 complex is an evolutionarily conserved multisubunit nuclease composed of the Mre11, Rad50, and Nbs1 proteins…