ATM Signaling Pathway

The ataxia telangiectasia-mutated gene (ATM) encodes a protein kinase that acts as a tumor suppressor. ATM activation by ionizing radiation damage to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2015
01220012015

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The purpose of this study was to evaluate the radiation-enhancing effect of sodium glycididazole, and the corresponding… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2012
2012
Ataxia telangiectasia mutated (ATM) protein kinase activation by DNA double-strand breaks (DSBs) requires the Mre11-Rad50-NBS1… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2011
2011
In a previous study, BO-1051, an N-mustard linked with a DNA-affinic molecule, was shown to target various types of cancer cell… (More)
Is this relevant?
2009
2009
Functional telomeres are required to maintain the replicative ability of cancer cells and represent putative targets for G… (More)
Is this relevant?
2008
2008
Biliary epithelial cells (BECs) of chronic non-suppurative destructive cholangitis (CNSDC) in primary biliary cirrhosis (PBC… (More)
Is this relevant?
2006
2006
Activation of the ATM DNA damage response pathway is commonly observed in a variety of early-stage neoplasias. It has been… (More)
Is this relevant?
2006
2006
The phytochemical indole-3-carbinol (I3C), from cruciferous vegetables such as broccoli, has been shown to elicit a potent anti… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The p53 tumor suppressor protein is phosphorylated and activated by several DNA damage-inducible kinases, such as ATM, and is a… (More)
Is this relevant?
Review
2004
Review
2004
The p53 tumor suppressor protein is phosphorylated and activated by several DNA damage-inducible kinases, such as ATM, and is a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The Nbs1 complex is an evolutionarily conserved multisubunit nuclease composed of the Mre11, Rad50, and Nbs1 proteins… (More)
Is this relevant?