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ATM Signaling Pathway

The ataxia telangiectasia-mutated gene (ATM) encodes a protein kinase that acts as a tumor suppressor. ATM activation by ionizing radiation damage to… Expand
National Institutes of Health

Papers overview

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2015
2015
The purpose of this study was to evaluate the radiation-enhancing effect of sodium glycididazole, and the corresponding… Expand
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2012
2012
Ataxia telangiectasia mutated (ATM) protein kinase activation by DNA double-strand breaks (DSBs) requires the Mre11-Rad50-NBS1… Expand
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2011
2011
In a previous study, BO-1051, an N-mustard linked with a DNA-affinic molecule, was shown to target various types of cancer cell… Expand
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Highly Cited
2009
Highly Cited
2009
Functional telomeres are required to maintain the replicative ability of cancer cells and represent putative targets for G… Expand
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2009
2009
AbstractAim:The aim of this study was to investigate the mechanism of pseudolaric acid B (PLAB)-induced cell cycle arrest in… Expand
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2008
2008
Biliary epithelial cells (BECs) of chronic non-suppurative destructive cholangitis (CNSDC) in primary biliary cirrhosis (PBC… Expand
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2006
2006
Activation of the ATM DNA damage response pathway is commonly observed in avariety of early-stage neoplasias. It has been… Expand
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2006
2006
The phytochemical indole-3-carbinol (I3C), from cruciferous vegetables such as broccoli, has been shown to elicit a potent anti… Expand
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Highly Cited
2004
Highly Cited
2004
The p53 tumor suppressor protein is phosphorylated and activated by several DNA damage-inducible kinases, such as ATM, and is a… Expand
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Highly Cited
2001
Highly Cited
2001
The Nbs1 complex is an evolutionarily conserved multisubunit nuclease composed of the Mre11, Rad50, and Nbs1 proteins… Expand
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