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ATM Signaling Pathway
The ataxia telangiectasia-mutated gene (ATM) encodes a protein kinase that acts as a tumor suppressor. ATM activation by ionizing radiation damage to…
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National Institutes of Health
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34 relations
ABL1 wt Allele
ATM protein, human
ATM wt Allele
ATRIP protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Upregulation of BTF3 affects the proliferation, apoptosis, and cell cycle regulation in hypopharyngeal squamous cell carcinoma.
Yang Zhang
,
N. Gross
,
+4 authors
Zhigang Huang
Biomedicine & pharmacotherapy = Biomedecine…
2019
Corpus ID: 199550249
2016
2016
Sodium glycididazole enhances the radiosensitivity of laryngeal cancer cells through downregulation of ATM signaling pathway
Yuecan Zeng
,
R. Xing
,
+9 authors
R. Wu
Tumor Biology
2016
Corpus ID: 31145531
The purpose of this study was to evaluate the radiation-enhancing effect of sodium glycididazole, and the corresponding…
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2013
2013
Wip1 and ATM in tumor evolution: role for BRCA1
D. Filipponi
,
D. Bulavin
OncoTarget
2013
Corpus ID: 5212399
Sequential accumulation of mutations is a central event that drives the conversion of normal cells into cancer. The recent advent…
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2011
2011
Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway.
Li-Hsin Chen
,
C. Loong
,
+8 authors
S. Chiou
Biochemical Pharmacology
2011
Corpus ID: 25388241
2008
2008
Activation of ATM signaling pathway is involved in oxidative stress-induced expression of mito-inhibitory p21WAF1/Cip1 in chronic non-suppurative destructive cholangitis in primary biliary cirrhosis…
M. Sasaki
,
H. Ikeda
,
Y. Nakanuma
Journal of Autoimmunity
2008
Corpus ID: 37266543
2008
2008
Antisense MDM2 Enhances E2F1-Induced Apoptosis and the Combination Sensitizes Androgen-Dependent and Androgen-Independent Prostate Cancer Cells to Radiation
T. Udayakumar
,
P. Hachem
,
Mansoor M Ahmed
,
S. Agrawal
,
A. Pollack
Molecular Cancer Research
2008
Corpus ID: 18972488
We have previously shown in separate studies that MDM2 knockdown via antisense MDM2 (AS-MDM2) and E2F1 overexpression via…
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