ABL1 wt Allele

Known as: JTK7, c-ABL, v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 wt Allele 
Human ABL1 wild-type allele is located in the vicinity of 9q34.1 and is approximately 173 kb in length. This allele, which encodes proto-oncogene… (More)
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Serum RNases are known to be elevated in patients with cancer. Consequently, it is not clear whether human mRNA with sufficient… (More)
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Highly Cited
1999
Highly Cited
1999
The c-Abl tyrosine kinase localizes to the cytoplasm and plasma membrane in addition to the nucleus. However, there is little… (More)
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Highly Cited
1993
Highly Cited
1993
In Philadelphia chromosome-positive human leukemias, the c-abl proto-oncogene on chromosome 9 becomes fused to the bcr gene on… (More)
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Highly Cited
1990
Highly Cited
1990
Oncogenic activation of the proto-oncogene c-abl in human leukemias occurs as a result of the addition of exons from the gene bcr… (More)
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Highly Cited
1988
Highly Cited
1988
The P210bcr/abl protein is associated with virtually every case of human chronic myelogenous leukemia. Unlike the related P160gag… (More)
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Highly Cited
1986
Highly Cited
1986
Chronic myelogenous leukemia (CML) is a human disease associated with a consistent chromosomal translocation that results in… (More)
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Highly Cited
1985
Highly Cited
1985
The Philadelphia (Ph′) chromosome, an abnormal chromosome 22 (ref. 1), is one of the best-known examples of a specific human… (More)
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Highly Cited
1984
Highly Cited
1984
The v-abl protein is known to be a tyrosine-specific protein kinase. However, its normal cellular homolog, c-abl P150, is not… (More)
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Highly Cited
1983
Highly Cited
1983
The localization of cellular oncogenes near the break points of tumour-specific chromosomal aberrations suggests an involvement… (More)
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Highly Cited
1982
Highly Cited
1982
The transforming genes of oncogenic retroviruses are homologous to a group of evolutionary conserved cellular onc genes1. The… (More)
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