ABL1 gene

Known as: c-ABL, ABELSON STRAIN OF MURINE LEUKEMIA VIRUS, ABL1 
This gene is involved in cell adhesion, differentiation, division and stress response.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
02040608019772017

Papers overview

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2014
2014
In chronic myeloid leukemia (CML) patients, a breakpoint cluster region-Abelson (BCR-ABL1) value >10% at 3 months of therapy is… (More)
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Highly Cited
2013
Highly Cited
2013
BCR-ABL1 compound mutations can confer high-level resistance to imatinib and other ABL1 tyrosine kinase inhibitors (TKIs). The… (More)
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Highly Cited
2009
Highly Cited
2009
Recurrent gene fusions are a prevalent class of mutations arising from the juxtaposition of 2 distinct regions, which can… (More)
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2009
2009
Adult and child B-cell progenitor acute lymphoblastic leukemia (BCP-ALL) differ in terms of incidence and prognosis. These… (More)
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Highly Cited
2008
Highly Cited
2008
The Philadelphia chromosome, a chromosomal abnormality that encodes BCR-ABL1, is the defining lesion of chronic myelogenous… (More)
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Highly Cited
2005
Highly Cited
2005
The BCR-ABL1 fusion kinase is frequently associated with chronic myeloid leukemia and B-cell acute lymphoblastic leukemia but is… (More)
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Highly Cited
2005
Highly Cited
2005
The cellular targets of primary mutations and malignant transformation remain elusive in most cancers. Here, we show that… (More)
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Highly Cited
2004
Highly Cited
2004
In T-cell acute lymphoblastic leukemia (T-ALL), transcription factors are known to be deregulated by chromosomal translocations… (More)
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Highly Cited
1999
Highly Cited
1999
De novo methylation of CpG islands within the promoters of eukaryotic genes is often associated with their transcriptional… (More)
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1999
1999
Methylation of the proximal promoter of the ABL1 oncogene is a common epigenetic alteration associated with clinical progression… (More)
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