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ABL1 gene

Known as: c-ABL, ABELSON STRAIN OF MURINE LEUKEMIA VIRUS, ABL1 
This gene is involved in cell adhesion, differentiation, division and stress response.
National Institutes of Health

Related topics

Related topics

29 relations
ABL1 wt AlleleApoptosisBlast PhaseC-abl and ARG Tyrosine Kinase Protein Overexpression

Broader (1)

c-abl Proto-Oncogenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
c-Abl phosphorylates E6AP and regulates its E3 ubiquitin ligase activity.
In human papillomavirus (HPV)-infected cells, the p53 tumor suppressor is tightly regulated by the HPV-E6-E6AP complex, which… 
2006
2006
Physical and functional interaction between hMSH5 and c-Abl.
Despite being a member of the mismatch repair family of proteins, the biological functions of hMSH5 in human cells are presently… 
2004
2004
Coupling of RAFTK/Pyk2 kinase with c-Abl and their role in the migration of breast cancer cells.
Mitogen-induced changes in the actin cytoskeleton are accompanied by changes in the tyrosine phosphorylation of several proteins… 
Highly Cited
2003
Highly Cited
2003
Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl
Conventional cancer therapies are based on preferential killing of tumor cells by DNA damage. Previous work showed that, for… 
Highly Cited
1996
Highly Cited
1996
Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport.
The product of the c-abl protooncogene is a nonreceptor tyrosine kinase found in both the cytoplasm and the nucleus. We report… 
1996
1996
c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein
The c-ABL tyrosine kinase is activated following either the loss or mutation of its Src homology domain 3 (SH3), resulting in… 
Highly Cited
1996
Highly Cited
1996
Binding of A/T-rich DNA by Three High Mobility Group-like Domains in c-Abl Tyrosine Kinase*
The c-Abl tyrosine kinase has been shown previously to bind DNA. Using polymerase chain reaction-based binding site-selection… 
1993
1993
En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase.
Src homology region 2 (SH2) domains are present in many proteins involved in signal transduction. In nonreceptor protein tyrosine… 
1987
1987
Molecular cloning and serological characterization of an altered c-abl gene product produced in Ph1 CML patients.
The reciprocal translocation between human chromosomes 9 and 22, termed the Philadelphia chromosome (Ph1), is observed in more… 
1980
1980
Abelson murine leukemia virus: characterization of a polyprotein containing phosphorylated component(s) encoded by newly acquired sequences.
A previously described 120,000 dalton polyprotein, P120, encoded by the Abelson strain of murine leukemia virus (AbLV) is… 
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