Blast Phase

Known as: chronic myelocytic leukemia, blastic phase, Blast Phases, Crisis, Blast 
An advanced phase of chronic myelogenous leukemia. It is characterized by: 1. the presence of blasts in the peripheral blood or bone marrow that are… (More)
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Recently the World Health Organization (WHO), in collaboration with the European Association for Haematopathology and the Society… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The cause of chronic myeloid leukemia (CML) is a constitutively active BCR-ABL tyrosine kinase. Imatinib inhibits this… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The BCR-ABL tyrosine kinase inhibitor imatinib is effective in Philadelphia chromosome-positive (Ph-positive… (More)
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Highly Cited
2005
Highly Cited
2005
The oncogenic BCR/ABL kinase activity induces and maintains chronic myelogenous leukemia (CML). We show here that, in BCR/ABL… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND The progression of chronic myelogenous leukemia (CML) to blast crisis is supported by self-renewing leukemic stem… (More)
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Review
2004
Review
2004
Chronic myelogenous leukemia (CML) evolves from a chronic phase characterized by the Philadelphia chromosome as the sole genetic… (More)
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Highly Cited
2002
Highly Cited
2002
Through sequencing analysis of blood or bone marrow samples from patients with chronic myeloid leukemia, we identified BCR-ABL… (More)
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Highly Cited
2002
Highly Cited
2002
Blast crisis is the most advanced stage of chronic myelogenous leukemia (CML) and is highly refractory to therapy. CML is caused… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Chronic myelogenous leukemia (CML) is caused by the BCR-ABL tyrosine kinase, the product of the Philadelphia… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL, a constitutively activated tyrosine kinase, is the product of the Philadelphia chromosome. This enzyme is… (More)
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