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BCR-ABL Fusion Gene

Known as: BCR-ABL1 Fusion Gene, BCR/ABL1 Fusion Gene, BCR-ABL Oncogene 
A gene formed when pieces of chromosomes 9 and 22 break off and trade places. The ABL gene from chromosome 9 joins to the BCR gene on chromosome 22… 
National Institutes of Health

Related topics

Related topics

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BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315IBlast PhaseFusion Proteins, bcr-ablLeukemia, Myeloid, Accelerated Phase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
A complex three-way translocation with deletion of the TP53 gene in a blast crisis chronic myeloid leukemia patient.
Chronic myeloid leukemia (CML) is characterized by the Philadelphia (Ph) chromosome created by the reciprocal translocation t(9… 
2011
2011
The role of natural killer cells in chronic myeloid leukemia
Chronic myeloid leukemia is a neoplasia resulting from a translocation between chromosomes 9 and 22 producing the BCR-ABL hybrid… 
Review
2011
Review
2011
New insights into the pathogenesis of chronic myeloid leukaemia: towards a path to cure.
Chronic myeloid leukaemia (CML) is a myeloproliferative clonal disease arising at the level of a pluripotent stem cell. It is… 
2010
2010
A rare chronic myeloid leukemia case with Philadelphia chromosome, BCR-ABL e13a3 transcript and complex translocation involving four different chromosomes.
The so-called Philadelphia (Ph) chromosome is present in more than 90% of chronic myeloid leukemia (CML) patients. Around 5-10… 
Review
2008
Review
2008
Identification of parental chromosomes involved in translocations BCR-ABL, t(9;22) and PML-RARA, t(15;17).
Cells of blood and bone marrow often exhibit a genome- or ploidywise organization of the two haploid sets, representing… 
2007
2007
Mesenchymal stem cells in patients with chronic myelogenous leukaemia or bi-phenotypic Ph+ acute leukaemia are not related to the leukaemic clone.
BACKGROUND Human mesenchymal stem cells (MSCs) are thought to be multipotent cells which primarily reside in the bone marrow… 
1996
1996
Molecular demonstration of BCR/ABL fusion in two cases with chronic myeloproliferative disorder carrying variant Philadelphia t(14;22)(q32;q11).
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