ATM protein, human

Known as: ataxia telangiectasia mutated protein, human, ATM serine-threonine kinase protein, human, A-T Mutated 
Serine-protein kinase ATM (3056 aa, ~351 kDa) is encoded by the human ATM gene. This protein is involved in DNA damage-induced protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
05010019932017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Ataxia Telangiectasia Mutated (ATM) signaling is essential for the repair of a subset of DNA double-strand breaks (DSBs); however… (More)
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Highly Cited
2007
Highly Cited
2007
Cellular responses to DNA damage are mediated by a number of protein kinases, including ATM (ataxia telangiectasia mutated) and… (More)
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Highly Cited
2007
Highly Cited
2007
When telomeres are rendered dysfunctional through replicative attrition of the telomeric DNA or by inhibition of shelterin, cells… (More)
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Highly Cited
2006
Highly Cited
2006
Recent studies have indicated the existence of tumorigenesis barriers that slow or inhibit the progression of preneoplastic… (More)
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Highly Cited
2004
Highly Cited
2004
The ‘ataxia telangiectasia mutated’ (Atm) gene maintains genomic stability by activating a key cell-cycle checkpoint in response… (More)
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Highly Cited
2004
Highly Cited
2004
H2AX phosphorylation is an early step in the response to DNA damage. It is widely accepted that ATM (ataxia telangiectasia… (More)
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Highly Cited
2004
Highly Cited
2004
The hereditary disorder ataxia telangiectasia (A-T) is associated with striking cellular radiosensitivity that cannot be… (More)
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Highly Cited
2001
Highly Cited
2001
A very early step in the response of mammalian cells to DNA double-strand breaks is the phosphorylation of histone H2AX at serine… (More)
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Highly Cited
2000
Highly Cited
2000
Nijmegen breakage syndrome (NBS) is characterized by extreme radiation sensitivity, chromosomal instability and cancer. The… (More)
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Highly Cited
1998
Highly Cited
1998
In response to DNA damage and replication blocks, cells prevent cell cycle progression through the control of critical cell cycle… (More)
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