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recombinant soluble CD4

Known as: sT4 (recombinant), sT4, soluble T4 
A recombinant form of CD4 antigen with anti-HIV application. Recombinant soluble T4 antigen (rsT4) is derived from cell surface antigen CD4 lacking… 
National Institutes of Health

Papers overview

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1999
1999
The initial event in infection by the human immunodeficiency virus type 1 (HIV-1) is the interaction of the viral envelope… 
Highly Cited
1996
Highly Cited
1996
HIV-1-infected quiescent CD4+ cells harbor the virus in an inactive state until subsequent activation. The possibility that HIV-1… 
1994
1994
In vitro, low-passage clinical human immunodeficiency virus type 1 (HIV-1) isolates require up to 1000 times greater serum levels… 
Highly Cited
1993
Highly Cited
1993
We have selected an HXB2 variant which can replicate in the presence of a neutralizing human serum. Sequencing of the gp120… 
Highly Cited
1991
Highly Cited
1991
Quantitative infectivity assays were used to study how the blocking activity of soluble CD4 (sCD4) is affected by sCD4… 
Highly Cited
1990
Highly Cited
1990
We compared four preparations of recombinant HIV-1 envelope glycoprotein: mammalian (Chinese hamster ovary cells) gp120 (Celltech… 
1990
1990
Recombinant soluble CD4 (rCD4) has been shown to be an effective inhibitor of human immunodeficiency virus type 1 (HIV-1) and HIV… 
Highly Cited
1989
Highly Cited
1989
The CD4 molecule is a high-affinity cell-surface receptor for the human immunodeficiency virus (HIV-1)1 and a soluble truncated… 
Highly Cited
1989
Highly Cited
1989
A combination of antiviral therapies that target different sites in the human immunodeficiency virus type 1 (HIV-1) replicative…