Skip to search formSkip to main contentSkip to account menu

recombinant soluble human CD4 protein

Known as: rCD4 
A recombinant human soluble CD4 with antiviral activity. Recombinant human soluble CD4 has the amino terminus but not the T-cell binding domain of… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

CD4 Antigensrecombinant soluble CD4
CD4 geneT-Cell Surface Glycoprotein CD4, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
DNA-based immunization induces anti-CD4 antibodies directed primarily to native epitopes.
DNA-based immunization is one of the most promising strategies to induce protective immunity against a variety of pathogens… 
Highly Cited
1993
Highly Cited
1993
Human megakaryocytes have a CD4 molecule capable of binding human immunodeficiency virus-1.
Most human megakaryocytes (MGKs) express the CD4 antigen on their surface. Approximately 25% have a CD4 receptor density… 
1992
1992
Internal-image anti-idiotype HIV-1gp120 antibody in human immunodeficiency virus 1 (HIV-1)-seropositive individuals with thrombocytopenia.
Anti-CD4 antibody was found in 30% of human immunodeficiency virus (HIV-1)-seropositive thrombocytopenic patients compared with 5… 
1992
1992
Autoantibodies in HIV‐infected Hemophilia Patients against Different Epitopes on CD4+Lymphocytes and Recombinant CD4
We studied 684 sera obtained from 20 hemophilia patients with AIDS/AIDS‐related complex (ARC), 89 asymptomatic HIV+, 76 HIV… 
Highly Cited
1991
Highly Cited
1991
Deamidation of soluble CD4 at asparagine-52 results in reduced binding capacity for the HIV-1 envelope glycoprotein gp120.
High-performance cation-exchange chromatography of recombinant soluble CD4 (rCD4) allowed the resolution of four charge variants… 
1991
1991
Recombinant CD4-selected human immunodeficiency virus type 1 variants with reduced gp120 affinity for CD4 and increased cell fusion capacity
Variants of molecularly cloned human immunodeficiency virus type 1 (HIV-1) were analyzed following selection for the ability to… 
Highly Cited
1990
Highly Cited
1990
Enhancement of SIV infection with soluble receptor molecules.
The CD4 receptor on human T cells has been shown to play an integral part in the human immunodeficiency virus type 1 (HIV-1… 
1990
1990
Effects of recombinant soluble CD4 (rCD4) on HIV-1 infection of monocyte/macrophages.
Recombinant soluble CD4 (rCD4) was tested for its ability to block acute human immunodeficiency virus (HIV) infection in the U937… 
1990
1990
Inhibition of serum-enhanced HIV-1 infection of U937 monocytoid cells by recombinant soluble CD4 and anti-CD4 monoclonal antibody.
Mononuclear phagocytes can be infected with the human immunodeficiency virus type 1 (HIV-1). Although these cells express CD4… 
1990
1990
Preparation and characterization of conjugates of recombinant CD4 and deglycosylated ricin A chain using different cross-linkers.
In a previous study, we have demonstrated that conjugates containing soluble, recombinant human CD4 (rCD4) and the deglycosylated… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)