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recombinant soluble human CD4 protein
Known as:
rCD4
A recombinant human soluble CD4 with antiviral activity. Recombinant human soluble CD4 has the amino terminus but not the T-cell binding domain of…
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
CD4 Antigens
recombinant soluble CD4
CD4 gene
T-Cell Surface Glycoprotein CD4, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
DNA-based immunization induces anti-CD4 antibodies directed primarily to native epitopes.
R. Attanasio
,
K. Pehler
,
F. Scinicariello
FEMS Immunology & Medical Microbiology
1997
Corpus ID: 26039673
DNA-based immunization is one of the most promising strategies to induce protective immunity against a variety of pathogens…
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Highly Cited
1993
Highly Cited
1993
Human megakaryocytes have a CD4 molecule capable of binding human immunodeficiency virus-1.
Y. Kouri
,
W. Borkowsky
,
M. Nardi
,
S. Karpatkin
,
R. Basch
Blood
1993
Corpus ID: 24075245
Most human megakaryocytes (MGKs) express the CD4 antigen on their surface. Approximately 25% have a CD4 receptor density…
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1992
1992
Internal-image anti-idiotype HIV-1gp120 antibody in human immunodeficiency virus 1 (HIV-1)-seropositive individuals with thrombocytopenia.
S. Karpatkin
,
M. Nardi
,
Y. Kouri
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 43030961
Anti-CD4 antibody was found in 30% of human immunodeficiency virus (HIV-1)-seropositive thrombocytopenic patients compared with 5…
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1992
1992
Autoantibodies in HIV‐infected Hemophilia Patients against Different Epitopes on CD4+Lymphocytes and Recombinant CD4
V. Daniel
,
R. Weimer
,
G. Zettlmeissl
,
K. Langner
,
R. Zimmermann
,
G. Opelz
Vox Sanguinis
1992
Corpus ID: 22675452
We studied 684 sera obtained from 20 hemophilia patients with AIDS/AIDS‐related complex (ARC), 89 asymptomatic HIV+, 76 HIV…
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Highly Cited
1991
Highly Cited
1991
Deamidation of soluble CD4 at asparagine-52 results in reduced binding capacity for the HIV-1 envelope glycoprotein gp120.
G. Teshima
,
J. Porter
,
K. Yim
,
V. Ling
,
A. Guzzetta
Biochemistry
1991
Corpus ID: 1193952
High-performance cation-exchange chromatography of recombinant soluble CD4 (rCD4) allowed the resolution of four charge variants…
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1991
1991
Recombinant CD4-selected human immunodeficiency virus type 1 variants with reduced gp120 affinity for CD4 and increased cell fusion capacity
J. Mckeating
,
P. Balfe
,
Paul R. Clapham
,
R. Weiss
Journal of Virology
1991
Corpus ID: 25791190
Variants of molecularly cloned human immunodeficiency virus type 1 (HIV-1) were analyzed following selection for the ability to…
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Highly Cited
1990
Highly Cited
1990
Enhancement of SIV infection with soluble receptor molecules.
Jonathan S. Allan
,
J. Strauss
,
D. Buck
Science
1990
Corpus ID: 37936454
The CD4 receptor on human T cells has been shown to play an integral part in the human immunodeficiency virus type 1 (HIV-1…
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1990
1990
Effects of recombinant soluble CD4 (rCD4) on HIV-1 infection of monocyte/macrophages.
M. A. Harbison
,
J. Gillis
,
P. Pinkston
,
R. Byrn
,
R. Rose
,
S. Hammer
Journal of Infectious Diseases
1990
Corpus ID: 20143044
Recombinant soluble CD4 (rCD4) was tested for its ability to block acute human immunodeficiency virus (HIV) infection in the U937…
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1990
1990
Inhibition of serum-enhanced HIV-1 infection of U937 monocytoid cells by recombinant soluble CD4 and anti-CD4 monoclonal antibody.
M. Zeira
,
R. Byrn
,
J. Groopman
AIDS Research and Human Retroviruses
1990
Corpus ID: 28728109
Mononuclear phagocytes can be infected with the human immunodeficiency virus type 1 (HIV-1). Although these cells express CD4…
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1990
1990
Preparation and characterization of conjugates of recombinant CD4 and deglycosylated ricin A chain using different cross-linkers.
V. Ghetie
,
M. Till
,
+6 authors
E. Vitetta
Bioconjugate chemistry
1990
Corpus ID: 23607813
In a previous study, we have demonstrated that conjugates containing soluble, recombinant human CD4 (rCD4) and the deglycosylated…
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