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Human megakaryocytes have a CD4 molecule capable of binding human immunodeficiency virus-1.
TLDR
Human MGKs have a CD4 receptor capable of binding HIV-1, which can infect cells representative of the MGK lineage, as determined by anti-gp120 and anti-CD41 staining. Expand
Internal-image anti-idiotype HIV-1gp120 antibody in human immunodeficiency virus 1 (HIV-1)-seropositive individuals with thrombocytopenia.
TLDR
Patients with HIV-1 thrombocytopenia contain internal-image idiotype-anti-idiotype complexes that could be affecting CD4 cell number or function, inhibiting HIV-2 binding to CD4 cells or contributing to HIV- 1 thromBocytopensia. Expand
Expression of CD4 by human megakaryocytes.
TLDR
Some human megakaryocytes express CD4 on their surface that should be capable of binding the HIV-1 gp120 envelope protein and could serve as a portal of entry for HIV- 1. Expand
Identification and typing of herpes simplex viruses with monoclonal antibodies
TLDR
Examination of a limited number of ulcerative lesions revealed that indirect immunofluorescence and virus isolation were comparable in detecting herpes simplex virus. Expand
Inapparent genital herpes simplex infection in women attending a venereal disease clinic.
The purpose of this study was to determine the prevalence of asymptomatic genital infection with herpes simplex virus in women attending a venereal disease clinic in Puerto Rico. Genital samples wereExpand
In Vitro Susceptibility of 50 Non-β-Lactamase-Producing Neisseria gonorrhoeae Strains to 12 Antimicrobial Agents
TLDR
The gonococci isolated were notably resistant to penicillin, ampicillin, erythromycin, and tetracycline, whereas all of the strains were susceptible to the newer β-lactam agents cefoxitin and spectinomycin. Expand
B-cell subsets and platelet counts in HIV-1 seropositive subjects
TLDR
The high concentrations of IgM-containing immune complexes in HIV-1-positive patients with autoimmune disorders may be due to changes in the CD5-positive B-cell subset, which is implicated in several autoimmune disorders. Expand
Effect of penicillin and spectinomycin given for urethritis and cervicitis with Neisseria gonorrhoeae: high prevalence of penicillin-resistant isolates.
TLDR
Clinical results suggest TRO could be given for treatment of genital gonorrhoea in Puerto Rico due to the high prevalence of both chromosomally-mediated penicillin-resistant Neisseria gonor Rhoeae and peniillinase-producing Neissaria gonor rhoeae strains and the high rate of failure seen with the use of APPG. Expand
Production of a human anti-CD4 monoclonal antibody with antiidiotype to anti-HIV type 1 glycoprotein 120.
TLDR
The production of a human monoclonal antiidiotype antibody that inhibits binding of HIV-1 to CD4 and induces the production of antibody against anti-HIV-1 gp120 is indicated, without being an internal image antiidiotsype (Ab2 beta). Expand
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