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CD4 Antigens

Known as: T-Cell T4 Antigens, CD4 antigen, Antigens, CD4 [Chemical/Ingredient] 
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (1)

CD Antigens

Narrower (6)

CD4 (81-92)CD4-IgG1 hinge fusion protein, recombinantDAB389CD4T-Cell Surface Glycoprotein CD4, human
CD4 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD4 Expressing Cell CountCD4 Positive T LymphocytesCD4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Neonatal bacillus Calmette‐Guérin vaccination induces adult‐like IFN‐γ production by CD4+ T lymphocytes
The immaturity of the neonatal immune system in mice is associated with defective IFN‐γ production and Th2‐biased immune… 
Highly Cited
1998
Highly Cited
1998
Circulating CD8 T lymphocytes in human immunodeficiency virus-infected individuals have impaired function and downmodulate CD3 zeta, the signaling chain of the T-cell receptor complex.
Although human immunodeficiency virus (HIV)-infected subjects without acquired immunodeficiency syndrome have a high frequency of… 
Highly Cited
1998
Highly Cited
1998
Binding of Human Immunodeficiency Virus Type 1 to CD4 and CXCR4 Receptors Differentially Regulates Expression of Inflammatory Genes and Activates the MEK/ERK Signaling Pathway
ABSTRACT We have previously shown that binding of human immunodeficiency virus type 1 (HIV-1) virions to CD4 receptors stimulates… 
Highly Cited
1997
Highly Cited
1997
Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions…
Several members of the chemokine receptor family have recently been identified as coreceptors, with CD4, for entry of human… 
Highly Cited
1997
Highly Cited
1997
Human mast cells produce the CD4+ T lymphocyte chemoattractant factor, IL-16.
CD4+ T cell infiltration is known to occur in tissues at sites of mast cell activation. The molecules produced and released by… 
Highly Cited
1992
Highly Cited
1992
Identification of a CD4 binding site on the β2 domain of HLA-DR molecules
THE CD4 and CDS molecules are transmembrane glycoproteins expressed by functionally distinct subsets of mature T cells. CD4+ and… 
Highly Cited
1992
Highly Cited
1992
Human immunodeficiency virus type 2 infection and fusion of CD4-negative human cell lines: induction and enhancement by soluble CD4
We describe human immunodeficiency type 2 (HIV-2) strains which induce cell-to-cell fusion and infect certain CD4- human cell… 
Highly Cited
1987
Highly Cited
1987
Deficiency of the suppressor inducer subset of T lymphocytes in rheumatoid arthritis.
New monoclonal antibodies allow CD4 lymphocytes to be categorized into helper/inducer (HI) CD4+ 4B4+, and suppressor inducer (SI… 
Highly Cited
1986
Highly Cited
1986
Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicry.
Human immunodeficiency virus (HIV), the retrovirus that causes the acquired immunodeficiency syndrome, is cytopathic for CD4+ T… 
Highly Cited
1985
Highly Cited
1985
Perturbation of the T4 molecule transmits a negative signal to T cells
We investigated the functional role of the T4 molecule in the activation of T cells by OKT3. T4+ cells were induced to… 
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