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pyripyropene A

Known as: FO 1289A 
 
National Institutes of Health

Papers overview

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2017
2017
Approximately 300 microbial natural products in our library were screened for insecticidal activities against three species of… Expand
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2016
2016
A series of pyripyropene A-based compounds were designed and synthesized by opening the upper section of the A-ring, which… Expand
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2015
2015
Sterol O-acyltransferase 2 (SOAT2; also known as ACAT2) is considered as a new therapeutic target for the treatment or prevention… Expand
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2015
2015
Pyripyropene A (PPPA, 1) of fungal origin, a selective inhibitor of acyl-CoA:cholesterol acyltransferase 2 (ACAT2), proved orally… Expand
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2014
2014
Pyripyropenes potently and selectively inhibit acyl-CoA:cholesterol acyltransferase 2 (ACAT-2). Among multiple isomers of… Expand
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2013
2013
In an effort to develop potent and selective inhibitors toward ACAT2, structure-activity relationship studies were carried out… Expand
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2013
2013
In an effort to develop potent and selective inhibitors toward ACAT2, structure-activity relationship studies were carried out… Expand
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2011
2011
OBJECTIVE Pyripyropene A (PPPA) of fungal origin is the first compound that has been found to strongly and selectively inhibit… Expand
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2011
2011
Pyripyropenes are potent inhibitors of acyl-CoA:cholesterol acyltransferase, which were initially discovered to be produced by… Expand
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2008
2008
Targeted deletion of acyl-CoA:cholesterol acyltransferase 2 (ACAT2) (A2), especially in the liver, protects hyperlipidemic mice… Expand
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