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pyripyropene A

Known as: FO 1289A 
National Institutes of Health

Papers overview

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2017
2017
Approximately 300 microbial natural products in our library were screened for insecticidal activities against three species of… Expand
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2015
2015
Sterol O-acyltransferase 2 (SOAT2; also known as ACAT2) is considered as a new therapeutic target for the treatment or prevention… Expand
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2014
2014
Pyripyropene A (PPPA, 1) of fungal origin, a selective inhibitor of acyl-CoA:cholesterol acyltransferase 2 (ACAT2), proved orally… Expand
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2013
2013
In an effort to develop potent and selective inhibitors toward ACAT2, structure-activity relationship studies were carried out… Expand
2013
2013
In an effort to develop potent and selective inhibitors toward ACAT2, structure-activity relationship studies were carried out… Expand
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Highly Cited
2011
Highly Cited
2011
Objective—Pyripyropene A (PPPA) of fungal origin is the first compound that has been found to strongly and selectively inhibit… Expand
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2011
2011
Pyripyropenes are potent inhibitors of acyl-CoA:cholesterol acyltransferase, which were initially discovered to be produced by… Expand
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2008
2008
Targeted deletion of acyl-CoA:cholesterol acyltransferase 2 (ACAT2) (A2), especially in the liver, protects hyperlipidemic mice… Expand
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2008
2008
  • J. Choi, M. Rho, +5 authors Y. Kim
  • Journal of microbiology and biotechnology
  • 2008
  • Corpus ID: 23660452
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) catalyzes cholesterol esterification and plays an important role in the… Expand
2005
2005
In nature there are several terpenoids with a characteristic gamma-dioxygenated system on the A ring, and many of them show… Expand