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pyripyropene A

Known as: FO 1289A 
National Institutes of Health

Papers overview

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2017
2017
Approximately 300 microbial natural products in our library were screened for insecticidal activities against three species of… 
2016
2016
A series of pyripyropene A-based compounds were designed and synthesized by opening the upper section of the A-ring, which… 
2015
2015
Sterol O-acyltransferase 2 (SOAT2; also known as ACAT2) is considered as a new therapeutic target for the treatment or prevention… 
2014
2014
Pyripyropene A (PPPA, 1) of fungal origin, a selective inhibitor of acyl-CoA:cholesterol acyltransferase 2 (ACAT2), proved orally… 
Highly Cited
2011
Highly Cited
2011
Objective—Pyripyropene A (PPPA) of fungal origin is the first compound that has been found to strongly and selectively inhibit… 
2011
2011
Pyripyropenes are potent inhibitors of acyl-CoA:cholesterol acyltransferase, which were initially discovered to be produced by… 
2008
2008
Targeted deletion of acyl-CoA:cholesterol acyltransferase 2 (ACAT2) (A2), especially in the liver, protects hyperlipidemic mice… 
2008
2008
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) catalyzes cholesterol esterification and plays an important role in the… 
2005
2005
In nature there are several terpenoids with a characteristic gamma-dioxygenated system on the A ring, and many of them show…