Author pages are created from data sourced from our academic publisher partnerships and public sources.
Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase)
- H. Miyadera, K. Shiomi, +7 authors S. O̅mura
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 6 January 2003
Enzymes in the mitochondrial respiratory chain are involved in various physiological events in addition to their essential role in the production of ATP by oxidative phosphorylation. The use of… Expand
In vitro and in vivo antimalarial activities of a non-glycosidic 18-membered macrolide antibiotic, borrelidin, against drug-resistant strains of Plasmodia.
Sir: In the course of our screening program to discover antimalarial antibiotics from soil microorganisms which are active against drug-resistant parasites in vitro and in vivo, we previously… Expand
Lariatins, Novel Anti-mycobacterial Peptides with a Lasso Structure, Produced by Rhodococcus jostii K01-B0171
Two anti-mycobacterial peptides with a lasso structure, named lariatins A and B, were separated by HP-20 and ODS column chromatographies and purified by HPLC from the culture broth of Rhodococcus… Expand
Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics.
The effect was studied of the fungal cyclodepsipeptide antibiotics beauvericin and seven distinct enniatins on acyl-CoA: cholesterol acyltransferase (ACAT) activity. In an enzyme assay using rat… Expand
Oryzihumus leptocrescens gen. nov., sp. nov.
- A. Kageyama, Y. Takahashi, T. Seki, H. Tomoda, S. O̅mura
- Medicine, Biology
- International journal of systematic and…
- 1 November 2005
Three novel strains were isolated from a soil sample collected in Japan using GPM agar plates supplemented with superoxide dismutase and/or catalase. The strains were Gram-positive,… Expand
Pyripyropenes, highly potent inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus.
Sir: Acyl-CoA: cholesterol acyltransferase (ACAT) is a key enzyme for cholesteryl ester accumulation in atherogenesis, lipoprotein formation in livers and cholesterol absorption from intestines.… Expand
Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure.
- M. Iwatsuki, H. Tomoda, R. Uchida, H. Gouda, S. Hirono, S. O̅mura
- Chemistry, Medicine
- Journal of the American Chemical Society
- 17 May 2006
Two antimycobacterial agents, lariatins A and B, were isolated from the culture broth of Rhodococcus sp. K01-B0171. Their structures were elucidated by spectral analysis and advanced protein chemical… Expand
Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171
- J. Inokoshi, Maki Matsuhama, Midori Miyake, H. Ikeda, H. Tomoda
- Biology, Medicine
- Applied Microbiology and Biotechnology
- 3 March 2012
The biosynthetic gene cluster for lariatins A and B, anti-mycobacterial peptide antibiotics with a unique “lasso” structure, was cloned from Gram-positive bacterium Rhodococcus jostii K01-B0171.… Expand
Inhibition of acyl-CoA synthetase by triacsins.
Triacsin A, 1-hydroxy-3-(E,E-2',4'-undecadienylidine) triazene and triacsin C, 1-hydroxy-3-(E,E,E-2',4',7'-undecatrienylidine) triazene are potent inhibitors of acyl-CoA synthetase (EC 22.214.171.124). The… Expand