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prostaglandin E synthase
Known as:
Prostaglandin H2 Prostaglandin E2 Isomerase
, PGE2 Isomerase
, Prostaglandin E Isomerase
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A membrane-associated prostaglandin E synthase that is induced by TUMOR SUPPRESSOR PROTEIN P53 and is involved in INFLAMMATION.
National Institutes of Health
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Related topics
Related topics
4 relations
PTGES gene
Prostaglandin E Synthase Measurement
Narrower (1)
Prostaglandin E Synthase, human
Broader (1)
Prostaglandin-E Synthases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase
Catherine E. Trebino
,
J. Stock
,
+16 authors
L. Audoly
Proceedings of the National Academy of Sciences…
2003
Corpus ID: 25786307
Prostaglandin (PG)E2 is a potent mediator of pain and inflammation, and high levels of this lipid mediator are observed in…
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Review
2001
Review
2001
Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily.
D. Sheehan
,
G. Meade
,
V. Foley
,
Catriona A. Dowd
Biochemical Journal
2001
Corpus ID: 2306517
The glutathione transferases (GSTs; also known as glutathione S-transferases) are major phase II detoxification enzymes found…
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Highly Cited
1998
Highly Cited
1998
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
M. Ricote
,
Andrew C. Li
,
T. Willson
,
C. Kelly
,
C. Glass
Nature
1998
Corpus ID: 4421986
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a member of the nuclear receptor superfamily of ligand-dependent…
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Highly Cited
1998
Highly Cited
1998
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
Chengyu Jiang
,
A. Ting
,
B. Seed
Nature
1998
Corpus ID: 4313485
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a member of the nuclear receptor family of transcription factors, a…
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Highly Cited
1997
Highly Cited
1997
Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential.
M. Tsujii
,
S. Kawano
,
R. Dubois
Proceedings of the National Academy of Sciences…
1997
Corpus ID: 35263777
Recent epidemiologic studies have shown a 40-50% reduction in mortality from colorectal cancer in individuals who take…
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Highly Cited
1995
Highly Cited
1995
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
M. Tsujii
,
R. Dubois
Cell
1995
Corpus ID: 11037319
Highly Cited
1993
Highly Cited
1993
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
J. Mitchell
,
P. Akarasereenont
,
C. Thiemermann
,
R. Flower
,
J. Vane
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 21509956
Constitutive cyclooxygenase (COX-1; prostaglandin-endoperoxide synthase, EC 1.14.99.1) is present in cells under physiological…
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Highly Cited
1993
Highly Cited
1993
Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
K. Yamagata
,
K. Andreasson
,
W. Kaufmann
,
C. Barnes
,
P. Worley
Neuron
1993
Corpus ID: 19996417
Highly Cited
1992
Highly Cited
1992
Human cyclooxygenase-2 cDNA.
T. Hla
,
K. Neilson
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 319054
Cyclooxygenase (Cox), also known as prostaglandin (PG) H synthase (EC 1.14.99.1), catalyzes the rate-limiting step in the…
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Highly Cited
1991
Highly Cited
1991
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.
Weilin Xie
,
J. Chipman
,
D. L. Robertson
,
R. Erikson
,
D. Simmons
Proceedings of the National Academy of Sciences…
1991
Corpus ID: 2228596
Rous sarcoma virus was shown to induce in chicken embryo fibroblasts (CEF) a 4.1-kilobase mRNA (designated CEF-147) encoding a…
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