prostaglandin E synthase

Known as: Prostaglandin H2 Prostaglandin E2 Isomerase, PGE2 Isomerase, Prostaglandin E Isomerase 
A membrane-associated prostaglandin E synthase that is induced by TUMOR SUPPRESSOR PROTEIN P53 and is involved in INFLAMMATION.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
We investigated the mechanisms by which inhibitors of prostaglandin G/H synthase-2 (PGHS-2; known colloquially as COX-2) increase… (More)
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Review
2004
Review
2004
Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most highly utilized classes of pharmaceutical agents in… (More)
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Highly Cited
2003
Highly Cited
2003
Prostaglandin (PG)E2 is a potent mediator of pain and inflammation, and high levels of this lipid mediator are observed in… (More)
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Review
2002
Review
2002
Prostaglandin E synthase (PGES), which converts cyclooxygenase (COX)-derived prostaglandin (PG)H2 to PGE2, occurs in multiple… (More)
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Highly Cited
2000
Highly Cited
2000
Here we report the molecular identification of membrane-bound glutathione (GSH)-dependent prostaglandin (PG) E(2) synthase (mPGES… (More)
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Highly Cited
1995
Highly Cited
1995
Prostaglandin endoperoxide synthase 2, also referred to as cyclooxygenase 2 (COX-2), is a key enzyme in the conversion of… (More)
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Highly Cited
1995
Highly Cited
1995
The prostaglandin endoperoxide H synthase isoform 2, cyclooxygenase 2 (COX-2), is induced at high levels in migratory and other… (More)
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Highly Cited
1995
Highly Cited
1995
Prostaglandin G/H synthase (PGHS), a key enzyme leading to the formation of prostaglandins, is the target of nonsteroidal… (More)
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Highly Cited
1991
Highly Cited
1991
Rous sarcoma virus was shown to induce in chicken embryo fibroblasts (CEF) a 4.1-kilobase mRNA (designated CEF-147) encoding a… (More)
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Highly Cited
1990
Highly Cited
1990
We report here that the bacterial lipopolysaccharide endotoxin induces human blood monocytes in a time- and dose-dependent manner… (More)
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