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prostaglandin E synthase

Known as: Prostaglandin H2 Prostaglandin E2 Isomerase, PGE2 Isomerase, Prostaglandin E Isomerase 
A membrane-associated prostaglandin E synthase that is induced by TUMOR SUPPRESSOR PROTEIN P53 and is involved in INFLAMMATION.
National Institutes of Health

Related topics

Related topics

4 relations
PTGES geneProstaglandin E Synthase Measurement

Narrower (1)

Prostaglandin E Synthase, human

Broader (1)

Prostaglandin-E Synthases

Papers overview

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Highly Cited
2009
Highly Cited
2009
Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
Two distinct helper T (TH) subsets, TH1 and TH17, mediate tissue damage and inflammation in animal models of various immune… 
Highly Cited
2003
Highly Cited
2003
Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis
We studied the febrile response in mice deficient in microsomal prostaglandin E synthase-1 (mPGES-1), an inducible terminal… 
Highly Cited
2002
Highly Cited
2002
Identification and characterization of a novel type of membrane-associated prostaglandin E synthase.
Membrane-associated prostaglandin E synthase (mPGE synthase) was previously purified to apparent homogeneity from the microsomal… 
Highly Cited
2001
Highly Cited
2001
Coexpression of Microsomal-Type Prostaglandin E Synthase with Cyclooxygenase-2 in Brain Endothelial Cells of Rats during Endotoxin-Induced Fever
Fever is triggered by an elevation of prostaglandin E2(PGE2) in the brain. However, the mechanism of its elevation remains… 
Highly Cited
1993
Highly Cited
1993
Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines.
Highly Cited
1993
Highly Cited
1993
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.
Highly Cited
1992
Highly Cited
1992
Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase.
Review
1991
Review
1991
Prostaglandin endoperoxide synthase: regulation of enzyme expression.
Highly Cited
1984
Highly Cited
1984
Low activities of glutathione-related enzymes as factors in the genesis of urinary bladder cancer.
A comparative study of reduced glutathione (GSH) concentrations and activities of GSH related-enzymes in urinary bladder… 
Highly Cited
1976
Highly Cited
1976
The importance of phospholipase-A2 in prostaglandin biosynthesis.
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