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PTGES gene

Known as: PGES, Prostaglandin E Synthase Gene, glutathione S-transferase 1-like 1 
This gene may play a role in TP53 induced apoptosis.
National Institutes of Health

Related topics

Related topics

4 relations
Oxidation-ReductionProstaglandin E Synthase, humanProstaglandin-E Synthasesprostaglandin E synthase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Involvement of PGE2 and the cAMP signalling pathway in the up-regulation of COX-2 and mPGES-1 expression in LPS-activated macrophages.
PG (prostaglandin) E2 plays an important role in the modulation of the immune response and the inflammatory process. In the… 
Highly Cited
2009
Highly Cited
2009
Neural stem/progenitor cells modulate immune responses by suppressing T lymphocytes with nitric oxide and prostaglandin E2
Review
2007
Review
2007
The cyclooxygenase‐2‐mediated prostaglandin signaling is causally related to epithelial carcinogenesis
Epidemiologic, pharmacologic, clinical, and experimental studies document the importance of prostaglandin (PG) signaling in… 
Highly Cited
2004
Highly Cited
2004
Platinum group element geochemistry of komatiites from the Alexo and Pyke Hill areas, Ontario, Canada
Highly Cited
2004
Highly Cited
2004
Balance Between PGD Synthase and PGE Synthase Is a Major Determinant of Atherosclerotic Plaque Instability in Humans
Objective—Inducible cyclooxygenase (COX-2) catalyzes the first step in prostanoid biosynthesis and is considered a… 
Highly Cited
2003
Highly Cited
2003
Disruption of the c-JUN-JNK Complex by a Cell-permeable Peptide Containing the c-JUN δ Domain Induces Apoptosis and Affects a Distinct Set of Interleukin-1-induced Inflammatory Genes*
The transcription factor activator protein (AP)-1 plays crucial roles in proliferation, cell death, and the immune response. c… 
Highly Cited
2000
Highly Cited
2000
Human Vascular Smooth Muscle Cells but Not Endothelial Cells Express Prostaglandin E Synthase
In a previous work, we postulated that endothelial cells possess only the following 2 enzymes involved in prostanoid synthesis… 
Review
2000
Review
2000
Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily.
The members of the MAPEG superfamily have been aligned and found to be distantly related, with a common pattern of hydropathy… 
Highly Cited
1979
Highly Cited
1979
Prostaglandin E modulation of the mitogenic response of human T cells. Differential response of T-cell subpopulations.
Prostaglandins (PG) of the E series, PGE(1) and PGE(2) (PGEs), can induce elevations of intracellular cyclic AMP (cAMP) among… 
Highly Cited
1977
Highly Cited
1977
Metabolism of prostaglandin endoperoxide in animal tissues.
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