polyketide synthase

Known as: Polyketide Synthases, PKS enzyme, Polyketide Synthases [Chemical/Ingredient] 
Large enzyme complexes composed of a number of component enzymes that are found in STREPTOMYCES which biosynthesize MACROLIDES and other polyketides.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Inflammation alters host physiology to promote cancer, as seen in colitis-associated colorectal cancer (CRC). Here, we identify… (More)
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Highly Cited
2009
Highly Cited
2009
Fungi produce numerous low molecular weight molecules endowed with a multitude of biological activities. However, mining the full… (More)
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Highly Cited
2005
Highly Cited
2005
Type I polyketide synthase (PKS) genes consist of modules ∼3–6 kb long, which encode the structures of 2-carbon units in… (More)
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Highly Cited
2004
Highly Cited
2004
Isolates of the rice blast fungus Magnaporthe grisea that carry the gene encoding Avirulence Conferring Enzyme1 (ACE1) are… (More)
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Review
2003
Review
2003
  • Ben Shen
  • Current opinion in chemical biology
  • 2003
Recent literature on polyketide biosynthesis suggests that polyketide synthases have much greater diversity in both mechanism and… (More)
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Highly Cited
2002
Highly Cited
2002
  • Jörn Piel
  • Proceedings of the National Academy of Sciences…
  • 2002
Many drug candidates from marine and terrestrial invertebrates are suspected metabolites of uncultured bacterial symbionts. The… (More)
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Highly Cited
1999
Highly Cited
1999
Fumonisins are toxins associated with several mycotoxicoses and are produced by the maize pathogen Gibberella fujikuroi mating… (More)
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Highly Cited
1996
Highly Cited
1996
Race T of the fungal pathogen Cochliobolus heterostrophus is highly virulent toward Texas male sterile (T) maize and differs from… (More)
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Highly Cited
1992
Highly Cited
1992
The avermectin (Av) polyketide synthase (PKS) and erythromycin (Er) PKS are encoded by modular repeats of DNA, but the genetic… (More)
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Highly Cited
1990
Highly Cited
1990
ERYTHROMYCIN A, a clinically important polyketide antibiotic, is produced by the Gram-positive bacterium Saccharopolyspora… (More)
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