Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 228,397,757 papers from all fields of science
Search
Sign In
Create Free Account
polyketide synthase
Known as:
Polyketide Synthases
, PKS enzyme
, Polyketide Synthases [Chemical/Ingredient]
Expand
Large enzyme complexes composed of a number of component enzymes that are found in STREPTOMYCES which biosynthesize MACROLIDES and other polyketides.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
17 relations
Narrower (8)
1,3,6,8-tetrahydroxynaphthalene synthase, Streptomyces coelicolor
6-Deoxyerythronolide-B Synthase
PKS15 protein, Mycobacterium tuberculosis H37Rv
Polyketide Synthase WA
Expand
Fatty-acid synthase
In Blood
Process of secretion
antagonists & inhibitors
Expand
Broader (1)
Multienzyme Complexes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Engineering of an "unnatural" natural product by swapping polyketide synthase domains in Aspergillus nidulans.
Ting Liu
,
Y. Chiang
,
Amber D. Somoza
,
B. Oakley
,
Clay C. C. Wang
Journal of the American Chemical Society
2011
Corpus ID: 5470484
An StcA-AfoE hybrid polyketide synthase (PKS), generated by swapping the AfoE (asperfuranone biosynthesis) SAT domain with the…
Expand
Highly Cited
2009
Highly Cited
2009
The biochemical basis for stereochemical control in polyketide biosynthesis.
C. Valenzano
,
R. Lawson
,
A. Chen
,
C. Khosla
,
D. Cane
Journal of the American Chemical Society
2009
Corpus ID: 207149371
One of the most striking features of complex polyketides is the presence of numerous methyl- and hydroxyl-bearing stereogenic…
Expand
Highly Cited
2007
Highly Cited
2007
An acridone‐producing novel multifunctional type III polyketide synthase from Huperzia serrata
Kiyofumi Wanibuchi
,
Ping Zhang
,
+5 authors
I. Abe
The FEBS Journal
2007
Corpus ID: 8089
A cDNA encoding a novel plant type III polyketide synthase was cloned and sequenced from the Chinese club moss Huperzia serrata…
Expand
Highly Cited
2006
Highly Cited
2006
Identification and analysis of the chivosazol biosynthetic gene cluster from the myxobacterial model strain Sorangium cellulosum So ce56.
O. Perlova
,
K. Gerth
,
O. Kaiser
,
A. Hans
,
R. Müller
Journal of Biotechnology
2006
Corpus ID: 19424599
Highly Cited
2004
Highly Cited
2004
Chalcomycin Biosynthesis Gene Cluster from Streptomyces bikiniensis: Novel Features of an Unusual Ketolide Produced through Expression of the chm Polyketide Synthase in Streptomyces fradiae
Shannon L. Ward
,
Zhihao Hu
,
+6 authors
L. Katz
Antimicrobial Agents and Chemotherapy
2004
Corpus ID: 12631552
ABSTRACT Chalcomycin, a 16-membered macrolide antibiotic made by the bacterium Streptomyces bikiniensis, contains a 2,3-trans…
Expand
Highly Cited
2002
Highly Cited
2002
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.
J. Ligon
,
S. Hill
,
+5 authors
T. Schupp
Gene
2002
Corpus ID: 2173826
Review
2001
Review
2001
Nitrogen-containing metabolites from marine cyanobacteria.
W H Gerwick
,
L. T. Tan
,
N. Sitachitta
The Alkaloids: Chemistry and Biology
2001
Corpus ID: 2921835
Highly Cited
1999
Highly Cited
1999
The first gene in the biosynthesis of the polyketide antibiotic TA of Myxococcus xanthus codes for a unique PKS module coupled to a peptide synthetase.
Y. Paitan
,
Gili Alon
,
E. Orr
,
E. Ron
,
Eugene Rosenberg
Journal of Molecular Biology
1999
Corpus ID: 37121409
The polyketide antibiotic TA is synthesized by the Gram negative bacterium Myxococcus xanthus in a multi-step process in which a…
Expand
Highly Cited
1995
Highly Cited
1995
Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2)
D. Bedford
,
E. Schweizer
,
D. Hopwood
,
C. Khosla
Journal of Bacteriology
1995
Corpus ID: 31066816
The multifunctional 6-methylsalicylic acid synthase gene from Penicillium patulum was engineered for regulated expression in…
Expand
Highly Cited
1992
Highly Cited
1992
6-Deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.
D. Bevitt
,
J. Cortés
,
S. Haydock
,
P. Leadlay
European Journal of Biochemistry
1992
Corpus ID: 35042441
Sequencing of the eryA region of the erythromycin biosynthetic gene cluster from Saccharopolyspora erythraea has revealed another…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE