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Two genes involved in the phase-variable phi C31 resistance mechanism of Streptomyces coelicolor A3(2)
TLDR
Nucleotide sequencing and functional analysis identified two genes, pglY and pglZ, required for the Pgl+ (phage-resistant) phenotype, and neither protein shows significant similarity to other known proteins, but PglY has a putative ATP/GTP binding motif. Expand
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.
From a cosmid library of Streptomyces cyanogenus S136, DNA fragments encompassing approximately 35 kb of the presumed landomycin biosynthetic gene cluster were identified and sequenced, revealing 32Expand
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tü22: sequence analysis and expression in a heterologous host.
TLDR
Putative functional assignments of the products of most of the newly discovered ORFs were made, including those of genes involved in the PKS and tailoring Steps in the biosynthesis of the granaticin aglycone, steps in the deoxy sugar pathway, and putative regulatory and export functions. Expand
Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2)
TLDR
The results suggest that it is possible to harness the molecular diversity of eukaryotic polyketid pathways by heterologous expression of biosynthetic genes in an easily manipulated model bacterial host in which prokaryotic aromatic and modular polyketide synthase genes are already expressed and recombined. Expand
Characterization of a gene conferring bialaphos resistance in Streptomyces coelicolor A3(2).
TLDR
Enzymic assay showed that the S. coelicolor bar gene product inactivates PPT by transfer of acetyl groups from acetyl CoA, indicating that sigma hrdD is not essential for recognition of these sequences. Expand
Functional Complementation of Pyran Ring Formation in Actinorhodin Biosynthesis in Streptomyces coelicolorA3(2) by Ketoreductase Genes for Granaticin Biosynthesis
ABSTRACT A mutation in actVI-ORF1, which controls C-3 reduction in actinorhodin biosynthesis by Streptomyces coelicolor, was complemented by gra-ORF5 and -ORF6 from the granaticin biosynthetic geneExpand
The names of the Australian grass-tree: Xanthorrhoea Sin. and Acoroides C. Kite (Xanthorrhoeaceae)
TLDR
The history of these names, their derivation and unacknowledged origins, and their application are discussed, and a new combination, Xanthorrhoea resinifera (D. Kite) E. Nelson & D. Bedford is made. Expand
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