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6-Deoxyerythronolide-B Synthase

Known as: 6 Deoxyerythronolide B Synthase, Synthase, 6-Deoxyerythronolide-B 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

polyketide synthase

Papers overview

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2016
2016
Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis.
2009
2009
Efficient experimental design and micro‐scale medium enhancement of 6‐deoxyerythronolide B production through Escherichia coli
The recent use of heterologous hosts to produce natural products has shown significant potential, although limitations still… 
2008
2008
6-deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli.
2004
2004
Manipulation and analysis of polyketide synthases.
2003
2003
Precursor-Directed polyketide biosynthesis in Escherichia coli.
2000
2000
An A245T Mutation Conveys on Cytochrome P450eryF the Ability to Oxidize Alternative Substrates*
Cytochrome P450eryF (CYP107A1), which hydroxylates deoxyerythronolide B in erythromycin biosynthesis, lacks the otherwise highly… 
1998
1998
Precursor-directed biosynthesis of 12-ethyl erythromycin.
1994
1994
Distribution of oxoacyl synthase homology sequences within Streptomyces DNA.
A genomic DNA sequence of Streptomyces strain ISP 5485 was cloned, sequenced and compared with corresponding information from… 
Highly Cited
1992
Highly Cited
1992
Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase
Previous studies of erythromycin biosynthesis have indicated that a cytochrome P-450 monooxygenase system is responsible for… 
1989
1989
The synthesis of polyoxygenated natural products via fully synthetic branched pyranose derivatives: application to the erythronolide problem
Abstract 
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