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Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase.
Fatty acid amide hydrolase (FAAH) catalyzes the hydrolysis of bioactive fatty acid amides and esters such as the endogenous cannabinoid receptor ligands, anandamide (N-arachidonoyl-ethanolamine) andExpand
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Trungapeptins A-C, cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula.
Trungapeptins A-C (1-3) were isolated from the marine cyanobacterium Lyngbya majuscula collected from Trung Province, Thailand. Their gross structures were elucidated by interpretation ofExpand
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The guineamides, novel cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula.
The guineamides (1-6) are novel cyclic depsipeptides isolated and characterized from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. The planar structures of these newExpand
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Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.
Curacin A (1) is a potent cancer cell toxin obtained from strains of the tropical marine cyanobacterium Lyngbya majuscula found in Curaçao. Its structure is unique in that it contains the sequentialExpand
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Nitrogen-containing metabolites from marine cyanobacteria.
Publisher Summary Marine cyanobacteria are extraordinarily prolific in their elaboration of complex and bioactive secondary metabolites. The principle biogenetic theme in the natural productsExpand
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Yanucamides A and B, two new depsipeptides from an assemblage of the marine cyanobacteria Lyngbya majuscula and Schizothrix species.
Yanucamides A (1) and B (2) were isolated from the lipid extract of a Lyngbya majuscula and Schizothrixsp. assemblage collected at Yanuca Island, Fiji. The structures of compounds 1 and 2 wereExpand
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Two new chymotrypsin inhibitors isolated from the Cyanobacterium Microcystis aeruginosa NIES-88.
Micropeptins 88-N (1) and 88-Y (2), new 3-amino-6-hydroxy-2-piperidone (Ahp)-containing cyclic depsipeptides, were isolated from Microcystis aeruginosa NIES-88. The structures were elucidated byExpand
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Poipuol, a new metabolite from a Hawaiian sponge of the genus Hyrtios.
A new metabolite, poipuol (1), was isolated from an undescribed marine sponge Hyrtios sp. collected in Kauai Island, Hawaii. The structure was determined from spectroscopic data.
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Biosynthetic Pathway and Origin of the Chlorinated Methyl Group in Barbamide and Dechlorobarbamide, Metabolites from the Marine Cyanobacterium Lyngbya majuscula
Abstract Structural and biosynthetic studies have been conducted on the barbamide class of molluscicidal agent. Dechlorobarbamide was isolated from a Curacao collection of the marine cyanobacteriumExpand
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Grenadadiene and grenadamide, cyclopropyl-containing fatty acid metabolites from the marine cyanobacterium Lyngbya majuscula.
Grenadadiene (1), debromogrenadiene (2), and grenadamide (3), three structurally unique cyclopropyl-containing metabolites, were isolated from the organic extract of a Grenada collection of theExpand
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