oncoprotein p21

Known as: MDA 6, WAF-1 Protein, CDK2 Associated Protein 20 kDa 
A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2017
05010019912017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Cancer cells acquire distinct metabolic adaptations to survive stress associated with tumour growth and to satisfy the anabolic… (More)
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Highly Cited
2010
Highly Cited
2010
Most solid tumors are aneuploid, and it has been proposed that aneuploidy is the consequence of an elevated rate of chromosome… (More)
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Highly Cited
2009
Highly Cited
2009
Reprogramming somatic cells to induced pluripotent stem (iPS) cells has been accomplished by expressing pluripotency factors and… (More)
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Highly Cited
2009
Highly Cited
2009
The pleiotropic lipid mediator sphingosine-1-phosphate (S1P) can act intracellularly independently of its cell surface receptors… (More)
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Highly Cited
2009
Highly Cited
2009
Aberrant overexpression of the miR-17-92 polycistron is strongly associated with B-cell lymphomagenesis. Recent studies have… (More)
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Highly Cited
2003
Highly Cited
2003
Although several genes that might mediate p53-induced apoptosis have been proposed, none have previously been shown to play an… (More)
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Highly Cited
1998
Highly Cited
1998
After DNA damage, many cells appear to enter a sustained arrest in the G2 phase of the cell cycle. It is shown here that this… (More)
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Highly Cited
1998
Highly Cited
1998
The p53 tumor suppressor gene product is known to act as part of a cell cycle checkpoint in G1 following DNA damage. In order to… (More)
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Highly Cited
1996
Highly Cited
1996
Signal transducers and activators of transcription (STAT) proteins can be conditionally activated in response to epidermal growth… (More)
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Highly Cited
1995
Highly Cited
1995
The transforming growth factor beta s (TGF-beta s) are a group of multifunctional growth factors which inhibit cell cycle… (More)
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