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oncoprotein p21

Known as: MDA 6, WAF-1 Protein, CDK2 Associated Protein 20 kDa 
A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN… 
National Institutes of Health

Related topics

Related topics

34 relations
ATM Signaling PathwayCDKN1A geneCDKN1A wt AlleleCalcineurin Pathway

Narrower (1)

Cdkn1a protein, rat

Broader (4)

Cell Cycle ProteinsEnzyme InhibitorsProtein Kinase InhibitorsProtein Kinases

Papers overview

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2016
2016
University of Dundee LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN 1 A gene in a p 53-dependent manner
Liver receptor homologue 1 (LRH-1) is an orphan nuclear receptor that has been implicated in the progression of breast… 
2012
2012
The proto-oncoprotein KR-POK represses transcriptional activation of CDKN1A by MIZ-1 through competitive binding
This corrects the article DOI: 10.1038/onc.2011.331 
2011
2011
Mechanism of action of p28, a first-in-class, non-HDM2 mediated peptide inhibitor of p53 ubiquitination.
e13513 Background: Exposure of a wide variety of wild type and mutated p53 cancer cells to a 28 aa peptide (p28) derived from… 
Review
2011
Review
2011
CDKN1B (cyclin-dependent kinase inhibitor 1 B )
Review on CDKN1B (cyclin-dependent kinase inhibitor 1 B ), with data on DNA, on the protein encoded, and where the gene is… 
2006
2006
Genistein Induces G 2 / M Cell Cycle Arrest and Apoptosis in Rat Neuroblastoma B 35 Cells
Background : The effect of genistein on different types of cells has been investigated. However, its effect on the nervous system… 
2004
2004
Antisense oligonucleotides and short interfering RNAs silencing the cyclin-dependent kinase inhibitor p21 improve proliferation of Duchenne muscular dystrophy patients’ primary skeletal myoblasts
Increased levels of the cyclin-dependent kinase inhibitor p21 associated with decreased myoblast proliferation may be involved in… 
2001
2001
Regulation of Gene Expression by 1 a , 25-Dihydroxyvitamin D 3 and Its Analog EB 1089 under Growth-Inhibitory Conditions in Squamous Carcinoma Cells
Analogs of 1a,25-dihydroxyvitamin D3 (1a, 25(OH)2D3) inhibit growth in vitro and in vivo of cells derived from a variety of… 
1997
1997
Nuclear localization of cyclin B 1 mediates its biological activity and is regulated by phosphorylation ( cytoplasmic retention signal y nuclear translocation )
M-phase promoting factor or maturation promoting factor, a key regulator of the G23M transition of the cell cycle, is a complex… 
1984
1984
Auditory evoked potentials in senescent forgetfulness.
Two evoked potential (EP) techniques and the selective reminding test were employed to investigate an apparently benign… 
1973
1973
Preimplantation stages from young and senescent golden hamsters: presence of succinic dehydrogenase and non-viable ova.
One of the characteristics of senescence in the female golden hamster is a sudden decline in the production of offspring. This…