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oncoprotein p21

Known as: MDA 6, WAF-1 Protein, CDK2 Associated Protein 20 kDa 
A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Cancer cells acquire distinct metabolic adaptations to survive stress associated with tumour growth and to satisfy the anabolic… Expand
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Highly Cited
2011
Highly Cited
2011
Transcription of long noncoding RNAs (lncRNAs) within gene regulatory elements can modulate gene activity in response to external… Expand
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Highly Cited
2010
Highly Cited
2010
The sustained activation of CDKN1A (p21/Waf1/Cip1) by a DNA damage response induces mitochondrial dysfunction and reactive oxygen… Expand
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Highly Cited
2009
Highly Cited
2009
Validating prognostic or predictive candidate genes in appropriately powered breast cancer cohorts are of utmost interest. Our… Expand
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Highly Cited
2009
Highly Cited
2009
Reprogramming somatic cells to induced pluripotent stem (iPS) cells has been accomplished by expressing pluripotency factors and… Expand
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Highly Cited
2005
Highly Cited
2005
In this study, we tested whether the human heart possesses a cardiac stem cell (CSC) pool that promotes regeneration after… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT Expression of the cyclin-dependent kinase inhibitor p21 is highly induced by many stresses, including exposure to short… Expand
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Highly Cited
1999
Highly Cited
1999
We have examined the effects of commonly used chemotherapeutic agents on human colon cancer cell lines in which the p53 pathway… Expand
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Highly Cited
1998
Highly Cited
1998
After DNA damage, many cells appear to enter a sustained arrest in the G2 phase of the cell cycle. It is shown here that this… Expand
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Highly Cited
1994
Highly Cited
1994
Using a yeast interaction screen to search for proteins that interact with cyclin D1-Cdk4, we identified a 27 kDa mouse protein… Expand
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