Protein Kinase Inhibitors

Known as: Inhibitors, Protein Kinase, Kinase Inhibitors, Protein, Protein Kinase Inhibitor 
Any substance that inhibits protein kinase, an enzyme that catalyzes the addition of a phosphate group to a protein and is active in many diverse… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Previous studies have shown that raising cytosolic calcium in myotubes induces increases in peroxisome proliferator-activated… (More)
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Highly Cited
2006
Highly Cited
2006
DNA double-strand breaks (DSB) are the most cytotoxic lesions induced by ionizing radiation and topoisomerase II poisons, such as… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To elucidate the roles of Rho-associated protein kinase (ROCK) in regulating intraocular pressure (IOP) and outflow… (More)
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Highly Cited
1999
Highly Cited
1999
The nucleosomal response refers to the rapid phosphorylation of histone H3 on serine 10 and HMG-14 on serine 6 that occurs… (More)
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Highly Cited
1998
Highly Cited
1998
The tetratricopeptide repeat (TPR) is a degenerate 34 amino acid sequence identified in a wide variety of proteins, present in… (More)
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Highly Cited
1998
Highly Cited
1998
Although phosphorylation of Thr-197 in the activation loop of the catalytic subunit of cAMP-dependent protein kinase (PKA) is an… (More)
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Highly Cited
1996
Highly Cited
1996
Mitogen-activated protein kinase (MAPK) is activated in cytoplasm in response to extracellular signals and then is translocated… (More)
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Highly Cited
1994
Highly Cited
1994
Rottlerin, a compound from Mallotus philippinensis, is shown to inhibit protein kinases with some specificity for PKC. To some… (More)
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Highly Cited
1992
Highly Cited
1992
When epithelial cell cultures are transferred from a medium with a normal extracellular calcium concentration (1-2 mM) to a… (More)
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Highly Cited
1989
Highly Cited
1989
THE phenomenon of long-term potentiation (LTP), a long lasting increase in the strength of synaptic transmission which is due to… (More)
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