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Protein Kinase Inhibitors

Known as: Inhibitors, Protein Kinase, Kinase Inhibitors, Protein, Protein Kinase Inhibitor 
Any substance that inhibits protein kinase, an enzyme that catalyzes the addition of a phosphate group to a protein and is active in many diverse… 
National Institutes of Health

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7-hydroxystaurosporineCDK6-associated protein p18Cyclin-Dependent Kinase 4 Inhibitor BCyclin-Dependent Kinase Inhibitor Proteins
In Bloodaspects of radiation effectschemical synthesisprotein kinase inhibitor activity

Papers overview

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2005
2005
The role of Ca2+ and cyclic AMP in the phosphorylation of rat-liver soluble proteins by endogenous protein kinases.
Rat liver soluble proteins were phosphorylated by endogenous protein kinase with [gamma-32P]ATP. Proteins were separated in… 
1999
1999
3′,5′‐Cyclic Guanosine Monophosphate Activates Mitogen‐Activated Protein Kinase in Rat Pinealocytes
Abstract : The role of 3′,5′‐cyclic guanosine monophosphate (cGMP) in the activation of mitogen‐activated protein kinases (MAPKs… 
1999
1999
Pharmacokinetics and pharmacodynamics of a novel protein kinase inhibitor, UCN-01
Purpose: 7-Hydroxystaurosporine (UCN-01) is a potent protein kinase inhibitor and is being developed as a novel anticancer agent… 
1984
1984
Injection of protein kinase inhibitor into cultured heart cells blocks calcium slow channels.
An inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP)-dependent protein kinase was injected into cultured heart cells… 
1984
1984
In vivo effects of microinjected alkaline phosphatase and its low molecular weight substrates on the first meiotic cell division in Xenopus laevis oocytes.
Xenopus laevis oocytes were microinjected with low molecular weight phosphoesters such as 2-glycerophosphate, phosphotyrosine… 
1983
1983
Evidence for the involvement of a cyclic AMP-independent protein kinase in the activation of soluble tyrosine hydroxylase from rat striatum.
Activation of rat striatal tyrosine hydroxylase [TyrOHase; tyrosine monooxygenase; L-tyrosine, tetrahydropteridine:oxygen… 
1977
1977
Regulation of protein kinase by vasopressin in renal medulla in situ.
Results of this study demonstrate that vasopressin activates protein kinase in intact renal medullary cells as detected by… 
1976
1976
Regulation of protein kinase in rat pineal: increased Vmax in supersensitive glands.
Protein kinase activity was examined in supernatants from super-sensitive and subsensitive rat pineal glands both in the presence… 
1975
1975
Ovarian cyclic adenosine monophosphate-dependent protein kinase activity: ontogeny and effect of gonadotropins.
The ontogeny of ovarian cyclic AMP-binding and protein kinase activities during the postnatal development of the rat, as well as… 
Highly Cited
1974
Highly Cited
1974
Reversible protein kinase activation of hormone-sensitive lipase from chicken adipose tissue.
Hormone-sensitive lipase partially purified from adipose tissue of laying hens was markedly activated by cyclic AMP-dependent…