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Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): a prospective observational study
Age-6 IQ correlated with IQs at younger ages, and IQ improved with age for infants exposed to any antiepileptic drug, consistent with other recent studies. Expand
Mapping anterior temporal lobe language areas with fMRI: A multicenter normative study
The Story-Math protocol provides a reliable method for activation of surgical regions of interest in the ATL and supports previous claims that conceptual processing involves both temporal lobes. Expand
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.
In utero exposure to valproate, as compared with other commonly used antiepileptic drugs, is associated with an increased risk of impaired cognitive function at 3 years of age, and this finding supports a recommendation thatValproate not be used as a first-choice drug in women of childbearing potential. Expand
Temporal lobectomy in children: cognitive outcome.
Preliminary data for establishing the risk of cognitive morbidity posed by temporal lobectomy performed during childhood is provided, with a slight improvement was significantly more likely to occur than a decline in global intellectual functioning. Expand
Classification Accuracy and Predictive Ability of The Medical Symptom Validity Test's Dementia Profile and General Memory Impairment Profile
The Dementia Profile correctly classified 36 patients with dementia and when only considering patients who failed symptom validity indices, sensitivity of the Dementsia Profile was 85%. Expand
IQ at 6 years after in utero exposure to antiepileptic drugs
Objective: To delineate the risk to child IQ associated with frequently prescribed antiepileptic drugs. Methods: Children born to women with epilepsy (n = 243) and women without epilepsy (n = 287)Expand
Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age.
A dose-dependent relationship is present for both lower verbal and non-verbal abilities with valproate and for lower verbal abilities with carbamazepine and preconceptional folate may improve cognitive outcomes. Expand
Unilateral cerebral inactivation produces differential left/right heart rate responses
The results are consistent with differential left/right cerebral hemispheric effects on autonomic function, and appear related to functional and anatomic asymmetries in both the central and peripheral nervous systems. Expand