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Protein Kinases

Known as: Protein Kinase, kinase protein, phosphorylase b kinase kinase 
A class of phosphotransferase proteins that posttranslationally modify protein substrates through the addition of phosphate groups.
National Institutes of Health

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Narrower (40)

3-Phosphoinositide Dependent Protein Kinase-1BSK5 protein, ArabidopsisCPK1 protein, ArabidopsisCRK1 protein, Arabidopsis
5'-AMP-Activated Protein Kinase Catalytic Subunit AlphaCell Cycle ProteinsEnzyme GeneIRAK3 protein, human

Papers overview

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Highly Cited
1987
Highly Cited
1987
Role of substrate in imparting calcium and phospholipid requirements to protein kinase C activation.
The role of substrate in influencing the cofactor requirements of the phospholipid- and Ca2+-dependent protein kinase C (PKC) was… 
Highly Cited
1986
Highly Cited
1986
Involvement of protein kinase C in the regulation of adrenocorticotropin release from rat anterior pituitary cells.
The involvement of protein kinase C in normal corticotroph function was studied by analysis of the effects of the phorbol ester… 
Highly Cited
1985
Highly Cited
1985
The role of calcium/phospholipid-dependent protein kinase in Leydig cell steroidogenesis.
Purified rat Leydig cell cytosol was found to contain a protein kinase which was dependent on the presence of both calcium and… 
Highly Cited
1982
Highly Cited
1982
Inhibition by melittin of phospholipid-sensitive and calmodulin-sensitive Ca2+-dependent protein kinases.
Effects of melittin, an amphipathic polypeptide, on various species of protein kinases were investigated. It was found that… 
Highly Cited
1980
Highly Cited
1980
Immunological distinction between guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases.
A guanosine 3':5'-monophosphate (cGMP)-dependent protein kinase was purified from bovine lung using 8-(6-aminohexylamino)-cAMP… 
Highly Cited
1980
Highly Cited
1980
Apparent constants for the interaction of regulatory and catalytic subunit of cAMP-dependent protein kinase I and II.
The apparent constants for the interaction of regu- latory (R) and catalytic (C) subunits of CAMP-depend-ent protein kinase types… 
Highly Cited
1979
Highly Cited
1979
Comparison of the substrate specificity of adenosine 3':5'-monophosphate- and guanosine 3':5'-monophosphate-dependent protein kinases. Kinetic studies using synthetic peptides corresponding to…
The substrate specificities of cyclic GMP-dependent and cyclic AMP-dependent protein kinases have been compared by kinetic… 
Highly Cited
1978
Highly Cited
1978
The modulator-dependent protein kinase. A multifunctional protein kinase activatable by the Ca2+-dependent modulator protein of the cyclic nucleotide system.
A protein kinase which depends on the simultaneous presence of Ca2+ and the modulator protein for its histone phosphorylation… 
Highly Cited
1977
Highly Cited
1977
Phosphorylation of rabbit and human erythrocyte membranes by soluble adenosine 3':5'-monophosphate-dependent and -independent protein kinases.
Previous reports from this laboratory and others have established that both the rabbit and human erythrocyte membranes contain… 
Highly Cited
1976
Highly Cited
1976
Stimulation of calcium accumulation in cardiac sarcolemma by protein kinase.
Sarcolemmal membranes isolated from guinea pig heart ventricles contained an ATP-dependent calcium-sequestering activity…