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Protein Kinases

Known as: Protein Kinase, kinase protein, phosphorylase b kinase kinase 
A class of phosphotransferase proteins that posttranslationally modify protein substrates through the addition of phosphate groups.
National Institutes of Health

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3-Phosphoinositide Dependent Protein Kinase-1BSK5 protein, ArabidopsisCPK1 protein, ArabidopsisCRK1 protein, Arabidopsis
5'-AMP-Activated Protein Kinase Catalytic Subunit AlphaCell Cycle ProteinsEnzyme GeneIRAK3 protein, human

Papers overview

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Highly Cited
1987
Highly Cited
1987
Role of substrate in imparting calcium and phospholipid requirements to protein kinase C activation.
The role of substrate in influencing the cofactor requirements of the phospholipid- and Ca2+-dependent protein kinase C (PKC) was… 
Highly Cited
1986
Highly Cited
1986
Involvement of protein kinase C in the regulation of adrenocorticotropin release from rat anterior pituitary cells.
The involvement of protein kinase C in normal corticotroph function was studied by analysis of the effects of the phorbol ester… 
Highly Cited
1982
Highly Cited
1982
Inhibition by melittin of phospholipid-sensitive and calmodulin-sensitive Ca2+-dependent protein kinases.
Effects of melittin, an amphipathic polypeptide, on various species of protein kinases were investigated. It was found that… 
Highly Cited
1980
Highly Cited
1980
Immunological distinction between guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases.
A guanosine 3':5'-monophosphate (cGMP)-dependent protein kinase was purified from bovine lung using 8-(6-aminohexylamino)-cAMP… 
Highly Cited
1979
Highly Cited
1979
Comparison of the substrate specificity of adenosine 3':5'-monophosphate- and guanosine 3':5'-monophosphate-dependent protein kinases. Kinetic studies using synthetic peptides corresponding to…
The substrate specificities of cyclic GMP-dependent and cyclic AMP-dependent protein kinases have been compared by kinetic… 
Highly Cited
1978
Highly Cited
1978
The modulator-dependent protein kinase. A multifunctional protein kinase activatable by the Ca2+-dependent modulator protein of the cyclic nucleotide system.
A protein kinase which depends on the simultaneous presence of Ca2+ and the modulator protein for its histone phosphorylation… 
Highly Cited
1976
Highly Cited
1976
Studies on the sites in histones phosphorylated by adenosine 3':5'-monophosphate-dependent and guanosine 3':5'-monophosphate-dependent protein kinases.
Adenosine 3':5'-monophosphate-dependent protein kinase (protein kinase A) purified from silkworm pupae phosphorylated five major… 
Highly Cited
1974
Highly Cited
1974
Mechanism of action of gonadotropin. IV. Cyclic adenosine monophosphate-dependent translocation of ovarian cytoplasmic cyclic adenosine monophosphate-binding protein and protein kinase to nuclear…
The interaction in vitro of cyclic [3H]AMP and a partially purified cyclic [3H] AMP-binding protein preparation from calf ovary… 
Highly Cited
1972
Highly Cited
1972
Protein Kinase and Specific Phosphate Acceptor Proteins Associated with Vaccinia Virus Cores
Incubation of purified vaccinia virus with γ-32P-adenosine triphosphate resulted in the incorporation of 32P into hot… 
Highly Cited
1971
Highly Cited
1971
Interconversion of cyclic nucleotide-activated and cyclic nucleotide-independent forms of a protein kinase from beef heart.
A protein kinase activated by cyclic nucleotides was purified from beef heart. Upon exposure to adenosine 3':5'-cyclic…