CDKN1A gene

Known as: cyclin-dependent kinase inhibitor 1A (CDKN1A) gene, CIP1, WILDTYPE p53-ACTIVATED FRAGMENT 1 
This gene is a regulator of cell cycle progression at the G1 phase of the cell cycle.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
We performed a meta-analysis of five genome-wide association studies to identify common variants influencing colorectal cancer… (More)
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Highly Cited
2004
Highly Cited
2004
Although previous studies demonstrate that appropriate Notch signaling is required during angiogenesis and in vascular… (More)
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Review
2003
Review
2003
The PI3K/Akt signal transduction cascade has been investigated extensively for its roles in oncogenic transformation. Initial… (More)
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Highly Cited
2003
Highly Cited
2003
Interactions between the proteasome inhibitor bortezomib and histone deacetylase inhibitors (HDIs) have been examined in Bcr/Abl… (More)
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Highly Cited
2000
Highly Cited
2000
Relative quiescence is a defining characteristic of hematopoietic stem cells, while their progeny have dramatic proliferative… (More)
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Highly Cited
1998
Highly Cited
1998
Overexpression of the receptor tyrosine kinase p185ErbB2 confers Taxol resistance in breast cancers. Here, we investigated the… (More)
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Highly Cited
1995
Highly Cited
1995
Cyclin-dependent kinases (Cdks) are positive regulators of cell proliferation, whereas Cdk inhibitors (CKIs) inhibit… (More)
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Highly Cited
1994
Highly Cited
1994
We here describe a rapid and simple expression screen method that has allowed us to isolate cDNAs coding for inhibitors of DNA… (More)
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Highly Cited
1993
Highly Cited
1993
The cyclin-dependent kinase Cdk2 associates with cyclins A, D, and E and has been implicated in the control of the G1 to S phase… (More)
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Highly Cited
1993
Highly Cited
1993
The ability of p53 to activate transcription from specific sequences suggests that genes induced by p53 may mediate its… (More)
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