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CDKN1A wt Allele

Known as: Cyclin-Dependent Kinase Inhibitor 1A wt Allele, CAP20, P21 
Human CDKN1A wild-type allele is located in the vicinity of 6p21.2 and is approximately 9 kb in length. This allele, which encodes cyclin-dependent… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
ABSTRACT The growth factor independent 1 (Gfi1) transcriptional regulator oncoprotein plays a crucial role in hematopoietic… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Induction of heme oxygenase-1 (HO-1) protects against diverse insults in the kidney and other tissues. We examined the… Expand
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Highly Cited
1999
Highly Cited
1999
Androgen is essential for the physiological maintenance of the integrity of prostatic epithelial cells, and castration causes the… Expand
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Review
1998
Review
1998
  • W. El-Deiry
  • Current topics in microbiology and immunology
  • 1998
  • Corpus ID: 2918275
In the short time since its discovery in 1993, the prototype cyclin-dependent kinase (CDK) inhibitor p21 (CIP1, Harper et al… Expand
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Highly Cited
1997
Highly Cited
1997
Exposure of mammalian cells to ionizing radiation (IR) induces a complex array of cellular responses including cell cycle arrest… Expand
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Highly Cited
1997
Highly Cited
1997
The p21(WAF1/CIP1/sdi1) gene product (WAF1) inhibits DNA replication in vitro (J. Chen, P. Jackson, M. Kirschner, and A. Dutta… Expand
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Highly Cited
1994
Highly Cited
1994
We here describe a rapid and simple expression screen method that has allowed us to isolate cDNAs coding for inhibitors of DNA… Expand
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Highly Cited
1994
Highly Cited
1994
The tumor suppressor p53 is a cell cycle checkpoint protein that contributes to the preservation of genetic stability by… Expand
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Highly Cited
1994
Highly Cited
1994
A newly cloned gene named wild-type p53-activated fragment 1 (WAF1; also known as p21, Pic-1, Cip-1, or SDI1) is directly… Expand
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Highly Cited
1993
Highly Cited
1993
The ability of p53 to activate transcription from specific sequences suggests that genes induced by p53 may mediate its… Expand
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